Evidence map›Paper›PMID 34839840›Full record

ArticleJournal of the International Neuropsychological Society : JINS2022

Neurodevelopmental Outcomes in Preterm Children with Sickle Cell Disease.

Sarah E Bills, Jeffrey Schatz, Erin Hunt, Sreya Varanasi, Julia Johnston, Jessica Bradshaw

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sarah E BillsDepartment of Psychology, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-9233-8716
Jeffrey SchatzDepartment of Psychology, University of South Carolina, Columbia, SC, USA.ORCID 0000-0002-5129-2344
Erin HuntDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
Sreya VaranasiDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
Julia JohnstonDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
Jessica BradshawDepartment of Psychology, University of South Carolina, Columbia, SC, USA.
University of South Carolina · US

Funding

Biomedical-Behavioral Interface: Prevention and Developmental Sciences TrainingT32GM081740 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI PRINZ, RONALD J · 2008 to 2022
$4.5M
Heart Defined Attention in Infancy: Predicting Social Communication and ASD SymptomologyK23MH120476 · NIMH · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BRADSHAW, JESSICA · 2019 to 2023
$939k
Neurobehavioral Determinants of Social Communication and Language Impairments in at - Risk InfantsR21DC017252 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI BRADSHAW, JESSICA · 2020 to 2022
$427k
NIDCD NIH HHS R21 DC017252NIGMS NIH HHS T32 GM081740NIMH NIH HHS K23 MH120476
6 · The paper itself

Abstract

objectivesTo explore the combined effect of pediatric sickle cell disease (SCD) and preterm birth on cognitive functioning.

methodsCognitive functioning was examined in children ages 6-8 with high risk SCD genotypes born preterm (

resultsChildren with elevated risk due to high risk SCD and preterm birth performed worse than other groups on a test of expressive language but not on tests that emphasize processing speed and working memory. There was a three-way interaction between preterm status, SCD risk, and abnormal screening outcome, which was largely driven by the increased likelihood of abnormal cognitive scores for children with high risk SCD born preterm.

conclusionsThe combination of SCD and preterm birth may confer increased risk for language deficits and elevated rates of abnormal cognitive screenings. This suggests that neurodevelopmental risk imparted by comorbid SCD and preterm birth may manifest as heterogenous, rather than specific, patterns of cognitive deficits. Future studies are needed to clarify the domains of cognitive functioning most susceptible to disease-related effects of comorbid SCD and preterm birth.

Indexed as

Anemia, Sickle CellCognition DisordersCognitive DysfunctionPremature BirthChildCognitionFemaleHumansInfant, Newbornbrain developmentchronic illnesscognitive functioningdouble hitneurocognitive riskPremature birth

Identifiers

PMID34839840
PMCPMC9148381
OpenAlexW3215624646

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.