Evidence map›Paper›PMID 34839704›Full record

ArticlePhilosophical transactions of the Royal Society of London. Series B, Biological sciences2022

Conjugative plasmid transfer is limited by prophages but can be overcome by high conjugation rates.

Claudia Igler, Lukas Schwyter, Daniel Gehrig, Carolin Charlotte Wendling

Open access · hybridAbstract read
In one paragraph

Article in Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. One Earth: The Equilibrium between the Human and the Bacterial Worlds.International journal of molecular sciences · 2023
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  13. Conjugative plasmid transfer is limited by prophages but can be overcome by high conjugation rates.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  14. Introduction: the secret lives of microbial mobile genetic elements.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Claudia IglerDepartment of Environmental Systems Science, Institute of Integrative Biology, ETH Zürich, Zurich, Switzerland.ORCID 0000-0001-7777-546X
Lukas SchwyterDepartment of Environmental Systems Science, Institute of Integrative Biology, ETH Zürich, Zurich, Switzerland.
Daniel GehrigDepartment of Environmental Systems Science, Institute of Integrative Biology, ETH Zürich, Zurich, Switzerland.
Carolin Charlotte WendlingDepartment of Environmental Systems Science, Institute of Integrative Biology, ETH Zürich, Zurich, Switzerland.ORCID 0000-0003-4532-7528
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance spread via plasmids is a serious threat to successfully fight infections and makes understanding plasmid transfer in nature crucial to prevent the rise of antibiotic resistance. Studies addressing the dynamics of plasmid conjugation have yet neglected one omnipresent factor: prophages (viruses integrated into bacterial genomes), whose activation can kill host and surrounding bacterial cells. To investigate the impact of prophages on conjugation, we combined experiments and mathematical modelling. Using

Indexed as

Conjugation, GeneticProphagesDrug Resistance, MicrobialEscherichia coliGene Transfer, HorizontalPlasmidsco-infectionconjugationhorizontal gene transfermobile genetic elementsplasmidsprophages

Identifiers

PMID34839704
PMCPMC8628080
OpenAlexW3217606805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.