Evidence map›Paper›PMID 34839398›Full record

Trial reportEuropean journal of nutrition2022

Adaptive thermogenesis after moderate weight loss: magnitude and methodological issues.

Catarina L Nunes, Filipe Jesus, Ruben Francisco, Catarina N Matias, Moonseong Heo, Steven B Heymsfield, Anja Bosy-Westphal, Luis B Sardinha, Paulo Martins, Cláudia S Minderico and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Effect of Time-Restricted Eating on Metabolic Adaptation in Adults With Severe Obesity During Early Phase of Weight Loss.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Catarina L NunesExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.ORCID http://orcid.org/0000-0002-8616-4625
Filipe JesusExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Ruben FranciscoExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Catarina N MatiasCIDEFES-Universidade Lusófona, 1749-024, Lisbon, Portugal.
Moonseong HeoDepartment of Public Health Sciences, Clemson University, Clemson, SC, USA.
Steven B HeymsfieldPennington Biomedical Research Center, Baton Rouge, LA, USA.
Anja Bosy-WestphalDepartment of Human Nutrition, Institute of Human Nutrition and Food Sciences, Christian-Albrechts University, Kiel, Germany.
Luis B SardinhaExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Paulo MartinsLaboratory of Sport Psychology, Faculdade de Motricidade Humana, Universidade de Lisboa, 1499-002, Cruz-Quebrada, Portugal.
Cláudia S MindericoExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal.
Analiza M SilvaExercise and Health Laboratory, CIPER, Faculdade Motricidade Humana, Universidade Lisboa, Estrada da Costa, 1499-002, Cruz-Quebrada, Portugal. analiza@fmh.ulisboa.pt.ORCID http://orcid.org/0000-0002-8984-8600

Funding

Fundação para a Ciência e a Tecnologia 2020.05397.BDFundação para a Ciência e a Tecnologia SFRH/BD/143725/2019Fundação para a Ciência e a Tecnologia UIDB/00447/2020
6 · The paper itself

Abstract

purposeThe aim of this study was (1) to assess AT through 13 different mathematical approaches and to compare their results; and (2) to understand if AT occurs after moderate WL.

methodsNinety-four participants [mean (SD); BMI, 31.1 (4.3) kg/m

resultsIG underwent a mean negative energy balance (EB) of 270 (289) kcal/day, p < 0.001), resulting in a WL of - 4.8 (4.9)% and an FM loss of - 11.3 (10.8)%. Regardless of approach, AT occurred in the IG, ranging from ~ - 65 to ~ - 230 kcal/day and three approaches showed significant AT in the CG.

conclusionsRegardless of approach, AT occurred after moderate WL in the IG. AT assessment should be standardized and comparisons among studies with different methodologies to assess AT must be avoided.

Indexed as

ObesityThermogenesisAdultBasal MetabolismBody CompositionCalorimetry, IndirectEnergy MetabolismFemaleHumansMaleWeight LossEnergy balanceMetabolic adaptationMetabolic slowingResting energy expenditure

Identifiers

PMID34839398

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.