Evidence map›Paper›PMID 34839374›Full record

ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2022

Mortality risk stratification in isolated severe traumatic brain injury using the revised cardiac risk index.

Maximilian Peter Forssten, Gary Alan Bass, Kai-Michael Scheufler, Ahmad Mohammad Ismail, Yang Cao, Niels Douglas Martin, Babak Sarani, Shahin Mohseni

Open access · hybridAbstract read
In one paragraph

Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Cardiac risk stratification and adverse outcomes in surgically managed patients with isolated traumatic spine injuries.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Maximilian Peter ForsstenSchool of Medical Sciences, Orebro University, 702 81, Örebro, Sweden.
Gary Alan BassSchool of Medical Sciences, Orebro University, 702 81, Örebro, Sweden.
Kai-Michael ScheuflerDepartment of Neurosurgery, Orebro University Hospital, 70185, Örebro, Sweden.
Ahmad Mohammad IsmailSchool of Medical Sciences, Orebro University, 702 81, Örebro, Sweden.
Yang CaoClinical Epidemiology and Biostatistics, School of Medical Sciences, Orebro University, Örebro, Sweden.
Niels Douglas MartinDivision of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, PA, 19104, USA.
Babak SaraniDivision of Trauma and Acute Care Surgery, George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Shahin MohseniSchool of Medical Sciences, Orebro University, 702 81, Örebro, Sweden. mohsenishahin@yahoo.com.ORCID http://orcid.org/0000-0001-7097-487X
Örebro University · SEGeorge Washington University · USÖrebro University Hospital · SEUniversity of Pennsylvania · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTraumatic brain injury (TBI) continues to be a significant cause of mortality and morbidity worldwide. As cardiovascular events are among the most common extracranial causes of death after a severe TBI, the Revised Cardiac Risk Index (RCRI) could potentially aid in the risk stratification of this patient population. This investigation aimed to determine the association between the RCRI and in-hospital deaths among isolated severe TBI patients.

methodsAll adult patients registered in the TQIP database between 2013 and 2017 who suffered an isolated severe TBI, defined as a head AIS ≥ 3 with an AIS ≤ 1 in all other body regions, were included. Patients were excluded if they had a head AIS of 6. The association between different RCRI scores (0, 1, 2, 3, ≥ 4) and in-hospital mortality was analyzed using a Poisson regression model with robust standard errors while adjusting for potential confounders, with RCRI 0 as the reference.

results259,399 patients met the study's inclusion criteria. RCRI 2 was associated with a 6% increase in mortality risk [adjusted IRR (95% CI) 1.06 (1.01-1.12), p = 0.027], RCRI 3 was associated with a 17% increased risk of mortality [adjusted IRR (95% CI) 1.17 (1.05-1.31), p = 0.004], and RCRI ≥ 4 was associated with a 46% increased risk of in-hospital mortality [adjusted IRR(95% CI) 1.46 (1.11-1.90), p = 0.006], compared to RCRI 0.

conclusionAn elevated RCRI ≥ 2 is significantly associated with an increased risk of in-hospital mortality among patients with an isolated severe traumatic brain injury. The simplicity and bedside applicability of the index makes it an attractive choice for risk stratification in this patient population.

Indexed as

Brain Injuries, TraumaticAdultHospital MortalityHumansRetrospective StudiesRisk AssessmentRisk FactorsMortalityRevised Cardiac Risk IndexRisk stratificationTraumatic brain injury

Identifiers

PMID34839374
PMCPMC9712303
OpenAlexW3215749877

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.