SynthesisEpilepsy & behavior : E&B2021
Epilepsy and the risk of severe coronavirus disease 2019 outcomes: A systematic review, meta-analysis, and meta-regression.
Synthesis in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Inflammatory bowel disease and COVID-19 outcomes: a meta-analysis.Scientific reports · 2022Pooled it
- Should patients with epilepsy be vaccinated against coronavirus disease 2019? A systematic review and meta-analysis.Epilepsy & behavior : E&B · 2022Pooled it
- Mortality from coronavirus disease 2019 (Covid-19) in patients with schizophrenia: A systematic review, meta-analysis and meta-regression.General hospital psychiatryPooled it
- COVID-19 vaccination uptake in children with epilepsy and vaccine hesitancy among their parents: a survey.European journal of pediatrics · 2024Article
- COVID-19 response in a long-term care facility for people with epilepsy.Epilepsia open · 2024Article
- Neurological diagnoses in hospitalized COVID-19 patients associated with adverse outcomes: A multinational cohort study.PLOS digital health · 2024Article
- Virus-Induced Epilepsy vs. Epilepsy Patients Acquiring Viral Infection: Unravelling the Complex Relationship for Precision Treatment.International journal of molecular sciences · 2024Review
- Article
- Pre-existing neurological conditions and COVID-19 co-infection: Data from systematic reviews, meta-analyses, and scoping reviews.Journal of the neurological sciences · 2023Review
- In-hospital outcomes in patients with and without epilepsy diagnosed with COVID-19-A cohort study.Epilepsia · 2023Article
- Article
- Safety and Tolerability of COVID-19 Vaccine in Children With Epilepsy: A Prospective, Multicenter Study.Pediatric neurology · 2023Article
- Article
- The association between epilepsy and COVID-19: analysis based on Mendelian randomization and FUMA.Frontiers in neuroscience · 2023Article
- Hematological, Inflammatory, Coagulation, and Oxidative/Antioxidant Biomarkers as Predictors for Severity and Mortality in COVID-19: A Prospective Cohort-Study.International journal of general medicine · 2023Article
- The effect of COVID-19 vaccination on epileptic seizures in patients with epilepsy: A clinical observation in China.Human vaccines & immunotherapeutics · 2022Observational
- Risk of hospitalization and death for COVID-19 in persons with epilepsy over a 20-month period: The EpiLink Bologna cohort, Italy.Epilepsia · 2022Article
- Impact of the COVID-19 pandemic on people with epilepsy: findings from the US arm of the COV-E study.Epilepsia open · 2022Article
- COVID-19 vaccination hesitancy among people with chronic neurological disorders: A position paper.European journal of neurology · 2022Article
- [Valproic Acid Could Help in the Fight Against COVID-19: a case-control study].Neurologia (Barcelona, Spain) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients with epilepsy experience seizures, which have been reported to increase and worsen during the coronavirus disease (COVID-19) pandemic. However, the association between epilepsy and COVID-19 outcomes remains unclear. The aim of this study was to analyze whether patients with epilepsy have an increased risk of having poor COVID-19 outcomes.
methodsWe comprehensively evaluated potential articles extracted from the medRxiv, Europe PMC, and PubMed databases until June 30, 2021, using selected keywords. All published studies on epilepsy and COVID-19 were selected. We used the Review Manager 5.4 and Comprehensive Meta-Analysis 3 software for statistical analysis.
resultsThirteen studies with 67,131 patients with COVID-19 were included in the analysis. Evaluation of the collated data revealed an association between epilepsy and increased severity of COVID-19 (OR, 1.69; 95%CI: 1.11-2.59; p = 0.010; I
conclusionsThe findings of this study suggest that patients with epilepsy are at risk of having poor COVID-19 outcomes. Patients with epilepsy need special attention and should be prioritized for administration of the COVID-19 vaccine. Registration details: PROSPERO (CRD42021264979).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.