Evidence map›Paper›PMID 34839214›Full record

SynthesisEuropean journal of radiology2021

Artificial intelligence for imaging-based COVID-19 detection: Systematic review comparing added value of AI versus human readers.

Christine Kriza, Valeria Amenta, Alexandre Zenié, Dimitris Panidis, Hubert Chassaigne, Patricia Urbán, Uwe Holzwarth, Aisha Vanessa Sauer, Vittorio Reina, Claudius Benedict Griesinger

Abstract readSystematic Review
In one paragraph

Synthesis in European journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Christine KrizaEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy. Electronic address: Christine.KRIZA@ec.europa.eu.
Valeria AmentaEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Alexandre ZeniéEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Dimitris PanidisEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Hubert ChassaigneEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Patricia UrbánEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Uwe HolzwarthEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Aisha Vanessa SauerEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Vittorio ReinaEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.
Claudius Benedict GriesingerEuropean Commission, Joint Research Centre (JRC), Via E. Fermi 2749 (TP 281) Ispra, Lombardy, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeA growing number of studies have examined whether Artificial Intelligence (AI) systems can support imaging-based diagnosis of COVID-19-caused pneumonia, including both gains in diagnostic performance and speed. However, what is currently missing is a combined appreciation of studies comparing human readers and AI.

methodsWe followed PRISMA-DTA guidelines for our systematic review, searching EMBASE, PUBMED and Scopus databases. To gain insights into the potential value of AI methods, we focused on studies comparing the performance of human readers versus AI models or versus AI-supported human readings.

resultsOur search identified 1270 studies, of which 12 fulfilled specific selection criteria. Concerning diagnostic performance, in testing datasets reported sensitivity was 42-100% (human readers, n = 9 studies), 60-95% (AI systems, n = 10) and 81-98% (AI-supported readers, n = 3), whilst reported specificity was 26-100% (human readers, n = 8), 61-96% (AI systems, n = 10) and 78-99% (AI-supported readings, n = 2). One study highlighted the potential of AI-supported readings for the assessment of lung lesion burden changes, whilst two studies indicated potential time savings for detection with AI.

conclusionsOur review indicates that AI systems or AI-supported human readings show less performance variability (interquartile range) in general, and may support the differentiation of COVID-19 pneumonia from other forms of pneumonia when used in high-prevalence and symptomatic populations. However, inconsistencies related to study design, reporting of data, areas of risk of bias, as well as limitations of statistical analyses complicate clear conclusions. We therefore support efforts for developing critical elements of study design when assessing the value of AI for diagnostic imaging.

Indexed as

Artificial IntelligenceCOVID-19Diagnostic ImagingHumansSARS-CoV-2

Identifiers

PMID34839214
PMCPMC8594127

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.