ArticleNeuroImage2021
High-resolution mapping and digital atlas of subcortical regions in the macaque monkey based on matched MAP-MRI and histology.
Article in NeuroImage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.
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Who cites it
45 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.
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- Brainana: an end-to-end preprocessing framework for macaque neuroimaging.bioRxiv : the preprint server for biology · 2026Article
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- Re-emergence of orientation coding in primate IT cortex and deep networks reveals functional hubs for visual processing.bioRxiv : the preprint server for biology · 2026Article
- Microscopy-informed structural connectivity mapping in the in vivo human brain via domain adaptation.bioRxiv : the preprint server for biology · 2026Article
- The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories.Journal of anatomy · 2026Article
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- Evaluating the image quality and brain microstructural exploration of mean apparent propagator-MRI-a pilot study.BMC medical imaging · 2026Article
- Asymmetric scaling of cerebellar cortex and deep nuclei reshapes input-output architecture across primates.Research square · 2026Article
- A Community Standard Multispecies Cell Atlas of the Basal Ganglia.bioRxiv : the preprint server for biology · 2026Article
- Nonuniform scaling of cerebellar cortical-nuclear architecture across primates revealed by cross-species atlases.bioRxiv : the preprint server for biology · 2026Article
- Advancing AADC deficiency therapy through MR-guided multisite delivery of AAV2-hAADC to dopaminergic and serotonergic pathways in the brainstem.Molecular therapy. Advances · 2026Article
- Electrophysiological Response of the Non-Anesthetized Primate Brain to Minimally Invasive Local Infrared Neural Stimulation in Chronic Experiments.Brain topography · 2025Article
- Transcranial ultrasound stimulation selectively enhances fronto-temporal context-guided memory.bioRxiv : the preprint server for biology · 2025Article
- The representation of object concepts across the brain.bioRxiv : the preprint server for biology · 2025Article
- Cellular basis for cortical network aging in primates.bioRxiv : the preprint server for biology · 2025Article
- In vivo submillimeter diffusion MRI dataset of 9 macaque brains curated for tractography.Scientific data · 2025Article
- Optimized AAV capsids for basal ganglia diseases show robust potency and distribution.Nature communications · 2025Article
- Imaging the structural connectome with hybrid MRI-microscopy tractography.Medical image analysis · 2025Article
- Shared and Unique Neural Codes for Biological Motion Perception in Humans and Macaque Monkeys.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
Corrections and comments
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Authors and funding
7 authors at 6 institutions in 1 country.
Funding
Abstract
Subcortical nuclei and other deep brain structures are known to play an important role in the regulation of the central and peripheral nervous systems. It can be difficult to identify and delineate many of these nuclei and their finer subdivisions in conventional MRI due to their small size, buried location, and often subtle contrast compared to neighboring tissue. To address this problem, we applied a multi-modal approach in ex vivo non-human primate (NHP) brain that includes high-resolution mean apparent propagator (MAP)-MRI and five different histological stains imaged with high-resolution microscopy in the brain of the same subject. By registering these high-dimensional MRI data to high-resolution histology data, we can map the location, boundaries, subdivisions, and micro-architectural features of subcortical gray matter regions in the macaque monkey brain. At high spatial resolution, diffusion MRI in general, and MAP-MRI in particular, can distinguish a large number of deep brain structures, including the larger and smaller white matter fiber tracts as well as architectonic features within various nuclei. Correlation with histology from the same brain enables a thorough validation of the structures identified with MAP-MRI. Moreover, anatomical details that are evident in images of MAP-MRI parameters are not visible in conventional T
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.