Evidence map›Paper›PMID 34838708›Full record

ArticleThe journal of allergy and clinical immunology. In practice2022

COVID-19 Infections and Asthma.

Philip A Palmon, Daniel J Jackson, Loren C Denlinger

Open access · hybridAbstract read
In one paragraph

Article in The journal of allergy and clinical immunology. In practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Role of Vitamins in the Pathogenesis of Asthma.International journal of molecular sciences · 2023
    Review
  7. [The problem of long/post-COVID in expert assessments].Unfallchirurgie (Heidelberg, Germany) · 2023
    Review
  8. Adolescent Views on Asthma Severity and Management During the COVID-19 Pandemic.Pediatric allergy, immunology, and pulmonology · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Chronic Rhinosinusitis and COVID-19.The journal of allergy and clinical immunology. In practice · 2022
    Review
  13. Perspectives in Respiratory Infections and the Lung.The journal of allergy and clinical immunology. In practice · 2022
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Philip A PalmonDivision of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wis.
Daniel J JacksonDivision of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wis; Division of Allergy, Immunology & Rheumatology, Department of Pediatrics, University of Wisconsin School of Medicine & Public Health, Madison, Wis.
Loren C DenlingerDivision of Allergy, Pulmonary & Critical Care Medicine, Department of Medicine, University of Wisconsin School of Medicine & Public Health, Madison, Wis. Electronic address: lcd@medicine.wisc.edu.
University of Wisconsin–Madison · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory syndrome coronavirus 2, which causes coronavirus disease 2019 (COVID-19), has infected more than 200 million and led to the deaths of more than 4.3 million people. Although there are known risk factors for severe disease, asthma was initially hypothesized to be a risk factor for severe disease given the association between asthma exacerbations and respiratory viral illnesses in general. Fortunately, clinical outcomes for patients with asthma overall are similar to those for patients without asthma, without convincing evidence that asthma is a risk factor for severe disease. This may be explained in part by the decreasing gradient of angiotensin-converting enzyme-2 receptor from the upper to lower respiratory epithelium and that aeroallergen-sensitized patients with asthma can have up to 50% reduction in angiotensin-converting enzyme-2 receptor expression. Vaccination for patients with asthma is recommended for all without clear contraindications. COVID-19-specific treatment options are available depending on the severity of disease. We caution the use of systemic corticosteroids in patients with asthma not requiring supplemental oxygen given an association with worse outcomes. Postacute COVID-19 syndrome or long-haul COVID does not appear to be more prevalent in the population with asthma, and a multidisciplinary approach to care is a reasonable option.

Indexed as

AsthmaCOVID-19HumansPost-Acute COVID-19 SyndromeRisk FactorsSARS-CoV-2AsthmaCorticosteroidsCOVID-19Vaccine

Identifiers

PMID34838708
PMCPMC8613003
OpenAlexW3215606845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.