Evidence map›Paper›PMID 34838661›Full record

ArticleResuscitation2022

Impact of the three COVID-19 surges in 2020 on in-hospital cardiac arrest survival in the United States.

Kashvi Gupta, Saket Girotra, Brahmajee K Nallamothu, Kevin Kennedy, Monique A Starks, Paul S Chan, American Heart Association's Get With the Guidelines®-Resuscitation Investigators (listed in Supplementary Appendix)

Abstract read
In one paragraph

Article in Resuscitation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Kashvi GuptaSaint Luke's Mid America Heart Institute, Kansas City, MO, United States; Department of Internal Medicine, University of Missouri Kansas City, Kansas City, MO, United States; Michigan Integrated Center for Health Analytics and Medical Prediction (MiCHAMP), University of Michigan, Ann Arbor, MI, United States.
Saket GirotraUniversity of Iowa Carver College of Medicine, Iowa City, IA, United States.
Brahmajee K NallamothuMichigan Integrated Center for Health Analytics and Medical Prediction (MiCHAMP), University of Michigan, Ann Arbor, MI, United States; Division of Cardiovascular Diseases, Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.
Kevin KennedySaint Luke's Mid America Heart Institute, Kansas City, MO, United States.
Monique A StarksDuke University School of Medicine and Duke Clinical Research Institute, Durham, NC, United States.
Paul S ChanSaint Luke's Mid America Heart Institute, Kansas City, MO, United States; Department of Internal Medicine, University of Missouri Kansas City, Kansas City, MO, United States. Electronic address: pchan@saint-lukes.org.
American Heart Association's Get With the Guidelines®-Resuscitation Investigators (listed in Supplementary Appendix)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have reported lower survival for in-hospital cardiac arrest (IHCA) during the initial COVID-19 surge. Whether the pandemic reduced IHCA survival during subsequent surges and in areas with lower COVID-19 rates is unknown.

methodsWithin Get-With-The-Guidelines®-Resuscitation, we identified 22,899 and 79,736 IHCAs during March to December in 2020 and 2015-2019, respectively. Using hierarchical regression, we compared risk-adjusted rates of survival to discharge in 2020 vs. 2015-19 during five COVID-19 periods: Surge 1 (March to mid-May), post-Surge 1 (mid-May to June), Surge 2 (July to mid-August), post-Surge 2 (mid-August to mid-October), and Surge 3 (mid-October to December). Monthly COVID-19 mortality rates for each hospital's county were categorized, per 1,000,000 residents, as very low (0-10), low (11-50), moderate (51-100), or high (>100).

resultsDuring each COVID-19 surge period in 2020, rates of survival to discharge for IHCA were lower, as compared with the same period in 2015-2019: Surge 1: adjusted OR: 0.81 (0.75-0.88); Surge 2: adjusted OR: 0.88 (0.79-0.97), Surge 3: adjusted OR: 0.79 (0.73-0.86). Lower survival was most pronounced at hospitals located in counties with moderate to high monthly COVID-19 mortality rates. In contrast, during the two post-surge periods, survival rates were similar in 2020 vs. 2015-2019: post-Surge 1: adjusted OR 0.93 (0.83-1.04) and post-Surge 2: adjusted OR 0.94 (0.86-1.03), even at hospitals with the highest county-level COVID-19 mortality rates.

conclusionsDuring the three COVID-19 surges in the U.S. during 2020, rates of survival to discharge for IHCA dropped substantially, especially in communities with moderate to high COVID-19 mortality rates.

Indexed as

Cardiopulmonary ResuscitationCOVID-19Heart ArrestHospitalsHumansPandemicsSARS-CoV-2Survival RateUnited StatesCardiac arrestCOVID-19In-hospital arrestOutcomesSurvival

Identifiers

PMID34838661
PMCPMC8611825

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.