Evidence map›Paper›PMID 34838125›Full record

ArticleTrials2021

Metacognitive therapy and work-focused interventions for patients on sick leave due to anxiety and depression: study protocol for a randomised controlled wait-list trial.

Kenneth Sandin, Ragne G H Gjengedal, Kåre Osnes, Marit Hannisdal, Torkil Berge, Jonas S R Leversen, Lars G Røv, Silje Endresen Reme, Suzanne Lagerveld, Roland Blonk and 4 more

Erratum issued Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03301922 (Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03301922 naunknown statusnot on this map

Metacognitive Therapy and Work Interventions for Patients on Sick Leave Due to Common Mental Disorders: A Randomized Waiting List Controlled Trial

TypeinterventionalSponsorNorwegian University of Science and TechnologyRan2017 to 2023Enrolled240ConditionsAnxiety, DepressionArmsMetacognitive therapy and work-focused interventions, Waiting list
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors.

Kenneth SandinDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway. kenneth.sandin@diakonsyk.no.ORCID http://orcid.org/0000-0002-1673-9606
Ragne G H GjengedalDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Kåre OsnesDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Marit HannisdalDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Torkil BergeDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Jonas S R LeversenDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Lars G RøvDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.
Silje Endresen RemeDepartment of Psychology, Faculty of Social Sciences, University of Oslo, Oslo, Norway.
Suzanne LagerveldDutch Institute for Employee Benefit Schemes (UWV), Amsterdam, The Netherlands.
Roland BlonkTNO Leiden, Leiden, The Netherlands.
Hans M NordahlFaculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.
Gemma ShieldsDivision of Population Health, Health Services Research, and Primary Care, University of Manchester, Manchester, UK.
Adrian WellsDivision of Population Health, Health Services Research, and Primary Care, University of Manchester, Manchester, UK.
Odin HjemdalDivision of Mental Health and Substance Abuse, Diakonhjemmet Hospital, Postboks 23 Vinderen, 0319, Oslo, Norway.

Funding

Stiftelsen Dam 2018FO201448
6 · The paper itself

Abstract

backgroundCommon mental disorders such as depression and anxiety are major contributors to the global burden of disease. Affected individuals suffer reduced quality of life, impaired functioning and reduced capacity to work. Maintaining employment is an important determinant for health and wellbeing, and the economic impact of depression and anxiety is a significant societal expense. Treatments providing effective symptom reduction and helping patients return to work (RTW) would thus have substantial public health benefits. The present study will explore the effectiveness of metacognitive therapy (MCT) and work-focused interventions on reducing symptoms and increasing RTW rates for patients on sick leave due to depression and anxiety.

methodsThe study is a randomised controlled wait-list trial (RCT; N = 240). The intervention group will receive protocol-based MCT and work-focused interventions immediately after inclusion. The control condition is a wait-list control group. All patients will receive up to 12 weekly sessions. The study context is a Norwegian outpatient clinic part of a national programme aimed at reducing sick leave. The co-primary outcomes are change in RTW and symptoms of depression and anxiety at the end of treatment. In addition to self-report, sick leave will also be collected from national registries from 2 years prior to intervention to 4 years after intervention. Symptoms of scores will be collected by self-report at pre- and post-treatment and at 6 and 12 months follow-up after treatment. A cost-effectiveness analysis will use total cost and quality-adjusted life-years as the secondary outcomes. DISCUSSION: There is broad consensus on the importance of identifying treatment that effectively reduces depression and anxiety symptoms and aids RTW. This study is an important contribution to the field as it is the first RCT on MCT and work-focused interventions for patients on sick leave due to anxiety and depression.

trial registrationClinicalTrials.gov NCT03301922 . Registered on October 4, 2017.

Indexed as

DepressionSick LeaveAnxietyAnxiety DisordersHumansQuality of LifeRandomized Controlled Trials as TopicAnxietyCost-effectivenessDepressionMetacognitive therapyRandomised controlled trialSick leaveWork-focused interventions

Identifiers

PMID34838125
PMCPMC8626756

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.