ArticleNutrition & metabolism2021
Prevalence and prognostic significance of malnutrition in diabetic patients with coronary artery disease: a cohort study.
Article in Nutrition & metabolism, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Comparison of adverse cardiovascular event endpoints between patients with diabetes and patients without diabetes based on coronary artery plaques: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2024Pooled it
- Prognostic Potential of the Controlling Nutritional Status (CONUT) Score in Predicting All-Cause Mortality and Major Adverse Cardiovascular Events in Patients With Coronary Artery Disease: A Meta-Analysis.Frontiers in nutrition · 2022Pooled it
- The Association Between Cholesterol, High-Density Lipoprotein, and Glucose Index and Mortality in Young and Middle-Aged Adults With Diabetes or Prediabetes: NHANES Data (1999-2018).Cardiology research · 2026Article
- Article
- Type 5 diabetes mellitus: nutritional-imprinted β-cell insufficiency, diagnostic gaps, and emerging therapeutic strategies.Frontiers in endocrinology · 2026Review
- Article
- Geriatric nutritional risk index as a predictor of outcomes in elderly patients undergoing percutaneous coronary intervention: An updated systematic review and meta-analysis.Pakistan journal of medical sciences · 2025Article
- Implications of prognostic nutritional index in predicting adverse outcomes of uncontrolled diabetic patients: a cohort study of the national health and nutrition examination survey from 2005 - 2018.Diabetology & metabolic syndrome · 2024Article
- Malnutrition Risk Among Hospitalized Patients With Type 2 Diabetes Mellitus and Its Association With Hospital Length.Public health challenges · 2024Article
- Correlation between serum sex hormone-binding globulin levels and nutrition indicators and malnutrition exposure risk in men and postmenopausal women with type 2 diabetes.BMC endocrine disorders · 2024Article
- Prognostic value of the prognostic nutritional index for patients with acute myocardial infarction undergoing percutaneous coronary intervention with variable glucose metabolism statuses: a retrospective cohort study.Diabetology & metabolic syndrome · 2023Article
- Association of prognostic nutritional index level and diabetes status with the prognosis of coronary artery disease: a cohort study.Diabetology & metabolic syndrome · 2023Article
- Article
- Malnutrition Is Associated with Diabetic Retinopathy in Patients with Type 2 Diabetes.Journal of diabetes research · 2023Article
- Prognostic value of creatinine-to-cystatin c ratio in patients with type 2 diabetes mellitus: a cohort study.Diabetology & metabolic syndrome · 2022Article
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Authors and funding
17 authors at 9 institutions in 1 country.
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Abstract
backgroundMalnutrition is associated with poor prognosis in cardiovascular disease patients or in diabetic patients. However, the relationship between malnutrition and clinical outcomes in diabetic patients with coronary artery disease (CAD) is not well known. The aim of this study is to report the prevalence and prognostic consequences of malnutrition in diabetic patients with CAD.
methodsIn this retrospective observational study, the Controlling Nutritional Status (CONUT) score applied to 12,898 consecutive diabetic patients with CAD. The association between malnutrition and long-term all-cause mortality was examined using Cox proportional hazards regression analysis.
resultsAccording to CONUT score, 60.5% patients suffered from malnutrition; 46.4%, 13.2%, and 0.9% patients had mild, moderate, and severe malnutrition, respectively. During a median follow-up of 4.88 (2.83-7.51) years, 1973 (15.3%) patients died. After adjustment for confounders, malnutrition was associated with significantly increased risk for long-term all-cause mortality (adjusted hazard ratio for mild malnutrition and moderate to severe malnutrition, respectively: 1.38 [95% confidence interval (CI) 1.07-1.77]; P value = 0.012 and 1.63 [95% CI 1.18-2.24]; P value = 0.003). A similar association was observed around subgroups.
conclusionsMalnutrition is common in diabetic patients with CAD and is strongly associated with increased mortality. It is necessary to adequately assess the nutritional status and take the effective nutritional guidance to improve the prognosis of diabetic patients with CAD.
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