Evidence map›Paper›PMID 34837949›Full record

ArticleBMC genomics2021

Characterisation of novel endogenous geminiviral elements in macadamia.

Mohamed C M Zakeel, Andrew D W Geering, John E Thomas, Olufemi A Akinsanmi

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Mohamed C M ZakeelThe University of Queensland, Queensland Alliance for Agriculture and Food Innovation, Centre for Horticultural Science, GPO Box 267, Brisbane, QLD, 4001, Australia. m.mohamedzakeel@uqconnect.edu.au.
Andrew D W GeeringThe University of Queensland, Queensland Alliance for Agriculture and Food Innovation, Centre for Horticultural Science, GPO Box 267, Brisbane, QLD, 4001, Australia.
John E ThomasThe University of Queensland, Queensland Alliance for Agriculture and Food Innovation, Centre for Horticultural Science, GPO Box 267, Brisbane, QLD, 4001, Australia.
Olufemi A AkinsanmiThe University of Queensland, Queensland Alliance for Agriculture and Food Innovation, Centre for Horticultural Science, GPO Box 267, Brisbane, QLD, 4001, Australia. o.akinsanmi@uq.edu.au.
ARC Centre of Excellence for Plant Success in Nature and Agriculture · AUAgriculture and Food · AUUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe presence of geminivirus sequences in a preliminary analysis of sRNA sequences from the leaves of macadamia trees with abnormal vertical growth (AVG) syndrome was investigated.

resultsA locus of endogenous geminiviral elements (EGE) in the macadamia genome was analysed, and the sequences revealed a high level of deletions and/or partial integrations, thus rendering the EGE transcriptionally inactive. The replication defective EGE in the macadamia genome indicates its inability to be the source of new viral infections and thus cause AVG or any other disease in macadamia. The EGE sequences were detected in two edible Macadamia species that constitute commercial cultivars and the wild germplasm of edible and inedible species of Macadamia. This strongly suggests that the integration preceded speciation of the genus Macadamia. A draft genome of a locus of EGE in Macadamia was developed. The findings of this study provide evidence to suggest the endogenization of the geminiviral sequences in the macadamia genome and the ancestral relationship of EGE with Macadamia in the Proteaceae family. Random mutations accumulating in the EGE inform that the sequence is evolving.

conclusionsThe EGE in Macadamia is inactive and thus not a direct cause of any diseases or syndromes including AVG in macadamia. The insertion of the EGE in the macadamia genome preceded speciation of the genus Macadamia.

Indexed as

GenomeMacadamiaFossilized viral sequencesGeminivirusProteaceae genomeRolling circle amplificationTranscriptional activity

Identifiers

PMID34837949
PMCPMC8626973
OpenAlexW3214860841

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.