Evidence map›Paper›PMID 34837775›Full record

ArticlePsychoneuroendocrinology2022

Childhood maltreatment, subjective social status, and health disparities in bereavement.

Michelle A Chen, Ryan L Brown, Jonathan Y Chen, Marcel A de Dios, Charles E Green, Cobi J Heijnen, Christopher P Fagundes

Abstract read
In one paragraph

Article in Psychoneuroendocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Prolonged grief disorder in later life: advancing our understanding of biopsychosocial mechanisms to guide future personalized interventions.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  2. Review
  3. Trajectories of depressive symptoms early in the course of bereavement: Patterns, psychosocial factors and risk of prolonged grief.Stress and health : journal of the International Society for the Investigation of Stress · 2024
    Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Michelle A ChenDepartment of Psychological Sciences, Rice University, 6100 Main St, Houston, TX 77005, USA. Electronic address: Michelle.A.Chen@rice.edu.
Ryan L BrownDepartment of Psychological Sciences, Rice University, 6100 Main St, Houston, TX 77005, USA.
Jonathan Y ChenMcGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston, TX 77030, USA; School of Public Health, The University of Texas Health Science Center at Houston, 1200 Pressler St, Houston, TX 77030, USA.
Marcel A de DiosDepartment of Psychological, Health, and Learning Sciences, University of Houston, 4800 Calhoun Rd, Houston, TX 77004, USA.
Charles E GreenDepartment of Symptom Research, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA.
Cobi J HeijnenDepartment of Pediatrics, McGovern Medical School, The University of Texas Health Science Center at Houston, 6431 Fannin St, Houston TX 77030, USA.
Christopher P FagundesDepartment of Psychological Sciences, Rice University, 6100 Main St, Houston, TX 77005, USA; Department of Behavioral Sciences, The University of Texas MD Anderson Cancer Center, 1515 Holcome Blvd, Houston, TX 77030, USA; Department of Psychiatry & Behavioral Sciences, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030, USA.

Funding

Convalescent Plasma to Limit Coronavirus Associated ComplicationsUL1TR003167 · NCATS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KARP, DANIEL D, MCPHERSON, DAVID D · 2019 to 2023
$45.3M
Individual differences in dementia spousal caregiver burden: A biobehavioral approach revisionR01AG062690 · NIA · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2019 to 2023
$4.3M
Project Heart: Biobehavioral Effects on Cardiovascular Risk for Bereaved SpousesR01HL127260 · NHLBI · RICE UNIVERSITY · PI FAGUNDES, CHRISTOPHER PAUL · 2015 to 2019
$4.1M
Adverse Childhood Experiences and Individual Differences among Dementia Spousal Caregivers: A Biobehavioral Approach to Stress Across the LifespanF31AG069439 · NIA · RICE UNIVERSITY · PI CHEN, MICHELLE A. · 2020 to 2021
$90k
NCATS NIH HHS UL1 TR003167NHLBI NIH HHS R01 HL127260NIA NIH HHS F31 AG069439NIA NIH HHS R01 AG062690
6 · The paper itself

Abstract

backgroundSpousal bereavement can lead to adverse health outcomes; however, not all widow(er)s experience the same degree of health problems. Thus, it is important to understand the contribution of disparities (e.g., childhood maltreatment and subjective social status) that may underlie adverse health outcomes that arise following bereavement.

methodsWe collected data from 130 spousally bereaved individuals at 3-time points (3 months post-loss, 4 months post-loss, and 6 months post-loss). Using mixed models, we assessed the interaction of childhood maltreatment, subjective social status, and time to predict changes in proinflammatory cytokine production, depressive symptoms, grief symptoms.

resultsWe found a significant interaction between childhood maltreatment, subjective social status, and time predicting proinflammatory cytokine production (beta > -0.01, p = 0.048), depressive symptoms (beta = 0.008, p = .010), and grief symptoms (beta = 0.001 p = .001).

conclusionThis study highlights the role of disparities related to childhood maltreatment and subjective social status on adverse health outcomes following spousal bereavement.

Indexed as

Adverse Childhood ExperiencesBereavementHealth Status DisparitiesSocial StatusSpousesCytokinesDepressionFemaleGriefHumansMaleSocial Determinants of HealthTime FactorsCytokinesBereavementChildhood maltreatmentDepressive symptomsGrief symptomsProinflammatory cytokine productionSubjective social status

Identifiers

PMID34837775
PMCPMC8702370

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.