ArticlePoultry science2022
Glycyrrhiza polysaccharides can improve and prolong the response of chickens to the Newcastle disease vaccine.
Article in Poultry science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 30 citations in OpenAlex.
- Glycyrrhiza polysaccharide inhibits feline infectious peritonitis virus infection screened by a recombinant virus expressing eGFP protein.BMC veterinary research · 2026Article
- Immune-Enhancing Effect ofAnimals : an open access journal from MDPI · 2026Article
- DietaryVeterinary world · 2026Article
- Identifying immunostimulatory herbal supplements that may flare autoimmune skin diseases: a systematic scoping review.Lupus science & medicine · 2025Article
- Natural vaccine adjuvants from traditional Chinese medicines: Mechanisms to applications.Acta pharmaceutica Sinica. B · 2025Review
- Mitigating impact of Glycyrrhiza glabra on virulent Newcastle disease virus challenge in chickens: clinical studies, histopathological alterations and molecular docking.Veterinary research communications · 2024Article
- Article
- Effects of glycyrrhiza polysaccharides on growth performance, meat quality, serum parameters and growth/meat quality-related gene expression in broilers.Frontiers in veterinary science · 2024Article
- Article
- Effects ofFrontiers in veterinary science · 2024Article
- Research progress on the mechanisms underlying poultry immune regulation by plant polysaccharides.Frontiers in veterinary science · 2023Review
- Progress of Studies on Plant-Derived Polysaccharides Affecting Intestinal Barrier Function in Poultry.Animals : an open access journal from MDPI · 2022Review
- Polysaccharides derived from Astragalus membranaceus and Glycyrrhiza uralensis improve growth performance of broilers by enhancing intestinal health and modulating gut microbiota.Poultry science · 2022Article
- Isolation, Characterization, Pharmacology and Biopolymer Applications of Licorice Polysaccharides: Review.Materials (Basel, Switzerland) · 2022Review
- Structure of a new glycyrrhiza polysaccharide and its immunomodulatory activity.Frontiers in immunology · 2022Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Licorice is a medicinal and food plant widely used to treat diseases and produce food additives, because of its unique chemical constituents like polysaccharides, flavones, and saponins. Glycyrrhiza Polysaccharides (GPS-1) are water-soluble neutral polysaccharides extracted from licorice. Currently, GPS-1 is administrated to chickens by gavage every d for 14 d to observe the impact of GPS-1 on the Newcastle disease vaccine. To determine the immunity of these chickens to NDV, blood serum levels of hemagglutinin-inhibition (HI) antibody, and immunoglobulins IgA and IgG were measured. Meanwhile, the expression levels of cytokines IL-2, IL-4, IL-17, and IFN-γ were measured to evaluate the degree of immune booster activity. The chickens' spleen and peripheral blood lymphocytes displayed a significant increase in the proportion of CD4+ and CD8+ T cells after booster treatments with GPS-1. The results indicated that GPS-1 had a significant, dose-dependent, immune-boosting effect which could enhance NDV vaccine immunity in chickens.
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