ArticleJournal of clinical laboratory analysis2022
ABC typing and extracellular enzyme production of Candida albicans isolated from Candida vulvovaginitis.
Article in Journal of clinical laboratory analysis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 16 citations in OpenAlex.
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- A Comparative Evaluation of Exoenzyme Production, Biofilm Development, and Cell Surface Hydrophobicity in Dominant Genotypes of Candida albicans.Journal of clinical laboratory analysis · 2025Article
- Investigating the presence of phospholipase and secreted aspartyle proteinase gene family in different genotypes of Candida albicans species.BMC research notes · 2025Article
- Vaginal mycobiome characteristics and therapeutic strategies in vulvovaginal candidiasis (VVC): differentiating pathogenic species and microecological features for stratified treatment.Clinical microbiology reviews · 2025Review
- Phenotypic and Molecular Characterization ofJournal of fungi (Basel, Switzerland) · 2025Article
- Nano-chitosan hydrogel alleviates Candida albicans-induced health alterations in Nile tilapia (Oreochromis niloticus): antioxidant response, neuro-behaviors, hepato-renal functions, and histopathological investigation.BMC veterinary research · 2025Article
- Genotypes analysis and antifungal susceptibility ofPakistan journal of medical sciences · 2024Article
- Investigation of the relationship between fluconazole susceptibility, proteinase activity andCurrent medical mycology · 2024Article
- Enzyme Production and Inhibitory Potential ofAntibiotics (Basel, Switzerland) · 2023Article
- Phenotypes characterization and ABC genotypes distribution of clinical Candida albicans isolates.Journal of clinical laboratory analysis · 2023Article
- Phenotype, genotype, and mating type determination in oral Candida albicans isolates from pediatric patients with neutropenia.Journal of clinical laboratory analysis · 2022Article
- ABC typing and extracellular enzyme production of Candida albicans isolated from Candida vulvovaginitis.Journal of clinical laboratory analysis · 2022Article
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Authors and funding
4 authors at 1 institution in 1 country.
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Abstract
backgroundCandida albicans is the most common and virulent genus Candida. Detection of virulence factors in this species plays an important role in the better understanding of pathogenesis and antifungal treatment. Molecular typing investigations are important in the epidemiological interpretation of infection. This study aimed to evaluate extracellular enzyme activity and genotyping of C. albicans species isolated from vulvovaginal samples.
methodsOne hundred and three vaginal C. albicans isolates were tested for esterase, phospholipase, proteinase, and hemolysin activities by specific media. Besides, the DNA of C. albicans isolates was extracted and amplified for ABC genotyping.
resultsThe highest enzyme production of C. albicans isolates was for proteinase (97.1%) and esterase (95.2%), whereas 59.2% of C. albicans isolates were negative for hemolysin secretion. Genotype C (83.5%) was the most frequent genotype followed by genotype B (12.6%) and genotype A (3.9%).
conclusionIt is concluded that genotype C was the predominant genotype in all examined vulvovaginal C. albicans isolates. Also, there was a significant difference between enzyme production in each genotype (except for proteinase).
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