Evidence map›Paper›PMID 34837561›Full record

ReviewNanoscale research letters2021

Advances and Challenges of Fluorescent Nanomaterials for Synthesis and Biomedical Applications.

Deli Xiao, Haixiang Qi, Yan Teng, Dramou Pierre, Perpetua Takunda Kutoka, Dong Liu

Abstract readReview
In one paragraph

Review in Nanoscale research letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
  2. Fluorescence Quenching Effects of Carbon Shells on EuInternational journal of molecular sciences · 2026
    Article
  3. Review
  4. Article
  5. Biomaterials for biomarker imaging and detection.Journal of advanced research · 2026
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Nanotheranostics: A Cutting-edge Technology for Cancer Management.Current pharmaceutical biotechnology · 2025
    Review
  13. Exploring Carbon Dots: Green Nanomaterials for Unconventional Lasing.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Deli Xiao *Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
Haixiang Qi *Department of Analytical Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
Yan TengDepartment of Analytical Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
Dramou PierreDepartment of Analytical Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
Perpetua Takunda KutokaDepartment of Analytical Chemistry, China Pharmaceutical University, Nanjing, 210009, China.
Dong LiuAnhui Engineering Laboratory for Conservation and Sustainable Utilization of Traditional Chinese Medicine Resources, School of Biological and Pharmaceutical Engineering, West Anhui University, West of Yunlu Bridge, Moon Island, Lu'an, 237012, Anhui, China. liudong3000@126.com.

Funding

National Natural Science Foundation of China No. 81402899
6 · The paper itself

Abstract

With the rapid development of nanotechnology, new types of fluorescent nanomaterials (FNMs) have been springing up in the past two decades. The nanometer scale endows FNMs with unique optical properties which play a critical role in their applications in bioimaging and fluorescence-dependent detections. However, since low selectivity as well as low photoluminescence efficiency of fluorescent nanomaterials hinders their applications in imaging and detection to some extent, scientists are still in search of synthesizing new FNMs with better properties. In this review, a variety of fluorescent nanoparticles are summarized including semiconductor quantum dots, carbon dots, carbon nanoparticles, carbon nanotubes, graphene-based nanomaterials, noble metal nanoparticles, silica nanoparticles, phosphors and organic frameworks. We highlight the recent advances of the latest developments in the synthesis of FNMs and their applications in the biomedical field in recent years. Furthermore, the main theories, methods, and limitations of the synthesis and applications of FNMs have been reviewed and discussed. In addition, challenges in synthesis and biomedical applications are systematically summarized as well. The future directions and perspectives of FNMs in clinical applications are also presented.

Indexed as

Biomedical applicationsCarbon dotsFluorescent nanomaterialsMetal nanoparticlesQuantum dotsSilica nanoparticles

Identifiers

PMID34837561
PMCPMC8626755

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.