Evidence map›Paper›PMID 34837296›Full record

ArticleChemphyschem : a European journal of chemical physics and physical chemistry2022

Comparative Hydrophobic Core Dynamics Between Wild-Type Amyloid-β Fibrils, Glutamate-3 Truncation, and Serine-8 Phosphorylation.

Liliya Vugmeyster, Dan Fai Au, Matthew C Smith, Dmitry Ostrovsky

Abstract read
In one paragraph

Article in Chemphyschem : a European journal of chemical physics and physical chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Persistence of Methionine Side Chain Mobility at Low Temperatures in a Nine-Residue Low Complexity Peptide, as Probed byChemphyschem : a European journal of chemical physics and physical chemistry · 2024
    Article
  3. Effect of Cross-Seeding of Wild-Type Amyloid-βThe journal of physical chemistry. B · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Liliya VugmeysterDepartment of Chemistry, University of Colorado Denver, Denver, CO, 80204, USA.ORCID 0000-0002-0491-5561
Dan Fai AuDepartment of Chemistry, University of Colorado Denver, Denver, CO, 80204, USA.
Matthew C SmithDepartment of Chemistry, University of Colorado Denver, Denver, CO, 80204, USA.
Dmitry OstrovskyDepartment of Mathematics, University of Colorado Denver, Denver, CO, 80204, USA.

Funding

Variant-specific dynamics of amyloid-b fibrilsR15GM111681 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI VUGMEYSTER, LILIYA · 2014 to 2021
$1.3M
CU Denver 1726947National High Magnetic Field LaboratoryNational Institutes of Health Grant 1R15-GM111681NIGMS NIH HHS R15 GM111681NIH HHS 1R15-GM111681NSF Cooperative Agreement NSF/DMR-1644779NSF grant 1726947State of FloridaU.S. Department of Energy
6 · The paper itself

Abstract

Post-translational modifications (PTMs) of amyloid-β (Aβ) species are implicated in the modulation of overall toxicities and aggregation propensities. We investigated the internal dynamics in the hydrophobic core of the truncated ΔE3 mutant fibrils of Aβ

Indexed as

Glutamic AcidSerineAmyloidAmyloid beta-PeptidesNuclear Magnetic Resonance, BiomolecularPeptide FragmentsPhosphorylationAmyloidAmyloid beta-PeptidesGlutamic AcidPeptide FragmentsSerineamyloid-beta fibrilsdeuterium NMRpost-translational modificationsrotameric jumpssolid-state NMR

Identifiers

PMID34837296
PMCPMC9484291

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.