Evidence map›Paper›PMID 34837204›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2022

Acoustic Angiography: Superharmonic Contrast-Enhanced Ultrasound Imaging for Noninvasive Visualization of Microvasculature.

Isabel G Newsome, Paul A Dayton

Abstract read
PubMed Publisher
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Current trends in the characterization and monitoring of vascular response to cancer therapy.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Isabel G NewsomeJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, USA.
Paul A DaytonJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, Raleigh, NC, USA. padayton@email.unc.edu.

Funding

Pre-doctoral Training Program in Integrative Vascular BiologyT32HL069768 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Christopher P. Mack · 2002 to 2026
$9.7M
Academic-Industrial Partnership for Translation of Acoustic AngiographyR01CA189479 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAYTON, PAUL A · 2014 to 2025
$4.7M
Micro-tumor detection by quantifying tumor-induced vascular abnormalities (PQ-13)R01CA170665 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAYTON, PAUL A · 2012 to 2015
$2.2M
Dual-frequency intravascular arrays for functional imaging of atherosclerosisR01EB015508 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI JIANG, XIAONING · 2012 to 2015
$2.0M
Acoustic Angiography Using Dual-Frequency and Ultrawideband CMUT ArraysR01EB026897 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI DAYTON, PAUL A, ORALKAN, OMER · 2018 to 2021
$1.9M
Quantitative Ultrasound Analysis of Vascular Morphology for Cancer AssessmentR44CA165621 · NCI · KITWARE, INC. · PI AYLWARD, STEPHEN R, DAYTON, PAUL A · 2015 to 2016
$1.3M
Toward Clinical Translation of Acoustic Angiography: Optimization of Microvascular Ultrasound Imaging on a Novel Dual-frequency ArrayF31CA243177 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI NEWSOME, ISABEL · 2019 to 2020
$74k
NCI NIH HHS F31 CA243177NCI NIH HHS R01 CA170665NCI NIH HHS R01 CA189479NCI NIH HHS R44 CA165621NHLBI NIH HHS T32 HL069768NIBIB NIH HHS R01 EB015508NIBIB NIH HHS R01 EB026897
6 · The paper itself

Abstract

Acoustic angiography is a contrast-enhanced ultrasound technique that relies on superharmonic imaging to form high-resolution, three-dimensional maps of the microvasculature. In order to obtain signal separation between tissue and contrast, acoustic angiography has been performed with dual-frequency transducers with nonoverlapping bandwidths. This enables a high contrast-to-tissue ratio, and the choice of a high frequency receiving element provides high resolution. In this chapter, we describe the technology behind acoustic angiography as well as the step-by-step implementation of this contrast enhanced microvascular imaging technique.

Indexed as

AngiographyAcousticsContrast MediaMicrobubblesMicrovesselsUltrasonographyContrast MediaAngiogenesisAngiographyContrast agentMicrobubblesMicrovasculatureUltrasound

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.