Evidence map›Paper›PMID 34837071›Full record

ArticleNature2021

Multiview confocal super-resolution microscopy.

Yicong Wu, Xiaofei Han, Yijun Su, Melissa Glidewell, Jonathan S Daniels, Jiamin Liu, Titas Sengupta, Ivan Rey-Suarez, Robert Fischer, Akshay Patel and 17 more

Abstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.

0numbers the graph read from it
0cells of the map it votes in
52citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

52 citing papers in PubMed.

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  19. Advances in Cellular and Molecular Biology Assays: A Review of Gold Standard Methods.International journal of innovative science and research technology · 2025
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors.

Yicong Wu *Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA. yicong.wu@nih.gov.ORCID http://orcid.org/0000-0002-8819-7527
Xiaofei Han *Laboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.
Yijun SuLaboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.
Melissa GlidewellApplied Scientific Instrumentation, Eugene, OR, USA.
Jonathan S DanielsApplied Scientific Instrumentation, Eugene, OR, USA.
Jiamin LiuAdvanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, MD, USA.
Titas SenguptaDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Ivan Rey-SuarezInstitute for Physical Science and Technology, University of Maryland, College Park, MD, USA.
Robert FischerCell and Developmental Biology Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Akshay PatelDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.ORCID http://orcid.org/0000-0001-6176-2496
Christian CombsNHLBI Light Microscopy Facility, National Institutes of Health, Bethesda, MD, USA.
Junhui SunLaboratory of Cardiac Physiology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Xufeng WuNHLBI Light Microscopy Facility, National Institutes of Health, Bethesda, MD, USA.
Ryan ChristensenLaboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.
Corey SmithDepartment of Radiology, University of Chicago, Chicago, IL, USA.
Lingyu BaoSection on Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.
Yilun SunLaboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6249-2704
Leighton H DuncanDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.
Jiji ChenAdvanced Imaging and Microscopy Resource, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-4426-3035
Yves PommierLaboratory of Molecular Pharmacology, Developmental Therapeutics Branch, Center for Cancer Research, National Institutes of Health, Bethesda, MD, USA.
Yun-Bo ShiSection on Molecular Morphogenesis, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-6330-0639
Elizabeth MurphyLaboratory of Cardiac Physiology, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
Sougata RoyDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, USA.ORCID http://orcid.org/0000-0002-2236-9277
Arpita UpadhyayaInstitute for Physical Science and Technology, University of Maryland, College Park, MD, USA.
Daniel Colón-RamosDepartment of Neuroscience and Department of Cell Biology, Yale University School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-0223-7717
Patrick La RiviereDepartment of Radiology, University of Chicago, Chicago, IL, USA.ORCID http://orcid.org/0000-0003-3415-9864
Hari ShroffLaboratory of High Resolution Optical Imaging, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD, USA.

Funding

Section on High Resolution Optical ImagingZIAEB000074 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI SHROFF, HARI · 2010 to 2022
$15.2M
WormGUIDES: A Resource for Global Understanding in Dynamic Embryonic SystemsR24OD016474 · OD · YALE UNIVERSITY · PI BAO, ZHIRONG, COLON-RAMOS, DANIEL A · 2013 to 2020
$6.5M
Powering the Brain: the Cell Biology of NeuroenergeticsDP1NS111778 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2018 to 2022
$5.9M
University of Chicago Initiative for Maximizing Student Development (IMSD) - Renewal 01R25GM109439 · NIGMS · UNIVERSITY OF CHICAGO · PI SCHWARTZ, NANCY B · 2014 to 2023
$5.7M
RESEARCH TRAINING IN MEDICAL PHYSICST32EB002103 · NIBIB · UNIVERSITY OF CHICAGO · PI ARMATO, SAMUEL G. · 2003 to 2019
$4.7M
Cellular and molecular mechanisms that temporally and spatially restrict synapticR01NS076558 · NINDS · YALE UNIVERSITY · PI COLON-RAMOS, DANIEL A · 2012 to 2022
$4.1M
Mechanisms of Cell Communication in Animal DevelopmentR35GM124878 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI ROY, SOUGATA · 2017 to 2021
$2.1M
PROTEIN-ASSOCIATED DNA BREAKS AS INDICATOR OF TOPOISOMERASE INHIBITIONZ01BC006150 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI POMMIER, YVES · 1996 to 2008
$1.5M
Supplement request for Microtubule regulation of actomyosin dynamics and force generation in T lymphocytesR01GM131054 · NIGMS · UNIV OF MARYLAND, COLLEGE PARK · PI UPADHYAYA, ARPITA · 2019 to 2022
$1.4M
Intramural NIH HHS Z01 BC006150Intramural NIH HHS ZIA EB000074NIBIB NIH HHS T32 EB002103NIGMS NIH HHS R01 GM131054NIGMS NIH HHS R25 GM109439NIGMS NIH HHS R35 GM124878NIH HHS R24 OD016474NINDS NIH HHS DP1 NS111778NINDS NIH HHS R01 NS076558
6 · The paper itself

Abstract

Confocal microscopy

Indexed as

Deep LearningAnimalsCaenorhabditis elegansCell Line, TumorDrosophila melanogasterHumansImaginal DiscsMiceMicroscopy, ConfocalMyoblastsOrgan SpecificitySingle-Cell AnalysisTissue Fixation

Identifiers

PMID34837071
PMCPMC8686173

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.