Evidence map›Paper›PMID 34836897›Full record

ArticleBMJ open2021

Online computer or therapist-guided cognitive behavioral therapy in university students with anxiety and/or depression: study protocol of a randomised controlled trial.

Anke Klein, N E Wolters, E J M Bol, J Koelen, L de Koning, S S M Roetink, J J van Blom, T Pronk, Claudia van der Heijde, Elske Salemink and 8 more

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Anke KleinAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands A.M.klein@uva.nl.ORCID 0000-0002-0914-0996
N E WoltersAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
E J M BolAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
J KoelenAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
L de KoningAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
S S M RoetinkAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
J J van BlomAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
T PronkAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
Claudia van der HeijdeDepartment of Research, Development and Prevention, Student Health Service, University of Amsterdam, Amsterdam, The Netherlands.
Elske SaleminkAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
Felix BolinskiDepartment of Clinical Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, The Netherlands.
Heleen RiperDepartment of Clinical Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, The Netherlands.
Eirini KaryotakiDepartment of Clinical Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, The Netherlands.ORCID 0000-0002-0071-2599
Pim CuijpersDepartment of Clinical Neuro- and Developmental Psychology, Amsterdam Public Health Research Institute, Vrije Universiteit Amsterdam, Amsterdam, Noord-Holland, The Netherlands.ORCID 0000-0001-5497-2743
S SchneiderClinical Child and Adolescent Psychology, Ruhr University Bochum, Bochum, Germany.
Ronald M RapeeCentre for Emotional Health, Macquarie University, Sydney, New South Wales, Australia.
Peter VonkDepartment of Research, Development and Prevention, Student Health Service, University of Amsterdam, Amsterdam, The Netherlands.
Reinout W WiersAddiction Development and Psychopathology (ADAPT)-lab, Developmental Psychology, Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands.
University of Amsterdam · NLGGD Amsterdam · NLVrije Universiteit Amsterdam · NLMacquarie University · AURuhr University Bochum · DEUtrecht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionEmerging adulthood is a phase in life that is associated with an increased risk to develop a variety of mental health disorders including anxiety and depression. However, less than 25% of university students receive professional help for their mental health reports. Internet-based cognitive behavioural therapy (iCBT) may entail useful interventions in a format that is attractive for university students. The aim of this study protocol is to test the effectiveness of a therapist-guided versus a computer-guided transdiagnostic iCBT programme with a main focus on anxiety and depression. METHODS AND ANALYSIS: University students with anxiety and/or depressive symptoms will be randomised to a (1) 7-week iCBT programme (excluding booster session) with therapist feedback, (2) the identical iCBT programme with computer feedback only or (3) care as usual. Participants in the care as usual condition are informed and referred to conventional care services and encouraged to seek the help they need. Primary outcome variables are self-reported levels of anxiety as measured with the General Anxiety Disorder-7 and self-reported levels of depression as measured with the Patient Health Questionnaire-9. Secondary outcomes include treatment adherence, client satisfaction, medical service use, substance use, quality of life and academic achievement. Assessments will take place at baseline (t1), midtreatment (t2), post-treatment (t3), at 6 months (t4) and 12 months (t5) postbaseline. Social anxiety and perfectionism are included as potentially important predictors of treatment outcome. Power calculations are based on a 3 (group) × 3 (measurement: pretreatment, midtreatment and post-treatment) interaction, resulting in an aimed sample of 276 participants. Data will be analysed based on intention-to-treat and per protocol samples using mixed linear models. ETHICS AND DISSEMINATION: The current study was approved by the Medical Ethics Review Committee (METC) of the Academic Medical Centre, Amsterdam, The Netherlands (number: NL64929.018.18). Results of this trial will be published in peer-reviewed journals. TRIAL REGISTRATION NUMBER: NL7328.

Indexed as

Cognitive Behavioral TherapyDepressionAdultAnxietyAnxiety DisordersHumansInternetQuality of LifeRandomized Controlled Trials as TopicStudentsTreatment OutcomeUniversitiesadult psychiatryanxiety disordersdepression & mood disorders

Identifiers

PMID34836897
PMCPMC8628330
OpenAlexW3217422225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.