Evidence map›Paper›PMID 34836581›Full record

ArticleFertility and sterility2021

Are worldwide sperm counts declining?

Niels Jørgensen, Dolores J Lamb, Hagai Levine, Alexander W Pastuszak, John T Sigalos, Shanna H Swan, Michael L Eisenberg

Abstract readEditorial
PubMed Publisher
In one paragraph

Article in Fertility and sterility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  20. Low-polarity untargeted metabolomic profiling as a tool to gain insight into seminal fluid.Metabolomics : Official journal of the Metabolomic Society · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Niels JørgensenUniversity Department of Growth and Reproduction, University of Copenhagen, Copenhagen, Denmark.
Dolores J LambDepartment of Urology, Weill Cornell Medical College, New York, New York; Englander Institute for Precision Medicine, Weill Cornell Medical College, New York, New York; Center for Reproductive Genomics, Weill Cornell Medical College, New York, New York.
Hagai LevineBraun School of Public Health and Community Medicine, Hadassah-Hebrew University, Jerusalem, Israel.
Alexander W PastuszakDivision of Urology, Department of Surgery, University of Utah Health Science Center, Salt Lake City, Utah.
John T SigalosDepartment of Urology, University of California Los Angeles, Los Angeles, California.
Shanna H SwanDepartment of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, New York.
Michael L EisenbergDepartment of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, California; Department of Urology, Stanford University School of Medicine, Stanford, California. Electronic address: eisenberg@stanford.edu.

Funding

Preclinical testing of a novel non-hormonal intravaginal ring to prevent pregnancy and sexually transmitted infectionsP50HD106793 · NICHD · POPULATION COUNCIL · PI FRIEDLAND, BARBARA A · 2021 to 2025
$11.1M
Targeting sperm-specific proteins during meiosis and sperm morphogenesisP01HD087157 · NICHD · BAYLOR COLLEGE OF MEDICINE · PI MATZUK, MARTIN M. · 2017 to 2021
$6.2M
Optimization and pre-clinical evaluation of ADCY10 inhibitorsP50HD100549 · NICHD · WEILL MEDICAL COLL OF CORNELL UNIV · PI BUCK, JOCHEN, LEVIN, LONNY R · 2019 to 2021
$6.0M
Improving the Diagnosis of Congenital Genitourinary Defects.R01DK078121 · NIDDK · WEILL MEDICAL COLL OF CORNELL UNIV · PI LAMB, DOLORES JEAN · 2007 to 2021
$4.8M
Characterization of the Role of NELL1 in the Predisposition to Peyronie's and Dupuytren's Diseases.K08DK115835 · NIDDK · UNIVERSITY OF UTAH · PI PASTUSZAK, ALEXANDER WOJCIECH · 2018 to 2020
$490k
NICHD NIH HHS P01 HD087157NICHD NIH HHS P50 HD100549NICHD NIH HHS P50 HD106793NIDDK NIH HHS K08 DK115835NIDDK NIH HHS R01 DK078121
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Data AnalysisGlobal HealthHumansInfertility, MaleMaleRandomized Controlled Trials as TopicSpermatozoaSperm CountSperm MotilityfertilityinfertilitySpermatozoa

Identifiers

PMID34836581

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.