Evidence map›Paper›PMID 34836504›Full record

Observational studyBMC anesthesiology2021

Impact of the SARS-CoV-2 (COVID19) pandemic on the morbidity and mortality of high risk patients undergoing surgery: a non-inferiority retrospective observational study.

Marta Caballero-Milán, Maria J Colomina, Leo A Marin-Carcey, Laura Viguera-Fernandez, Roser Bayona-Domenge, Sara Garcia-Ballester, Albert López-Farre, Leticia Ruiz-Buera, Maite Sanz-Iturbe, David Álvarez-Villegas and 7 more

Registry-linked trialOpen access · goldAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04780594 (Impact of the SARS-CoV-2), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04780594 completednot on this map

Impact of the SARS-CoV-2 (COVID-19) Pandemic on the Morbidity and Mortality of Patients Undergoing Surgery at Bellvitge University Hospital

TypeobservationalSponsorHospital Universitari de BellvitgeRan2020 to 2020Enrolled2,530ConditionsCovid19, Surgery--Complications, Nosocomial InfectionArmsThe study evaluates all surgical patients operated, both elective scheduled and emergent cases
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Marta Caballero-MilánDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain. marta.caballero@bellvitgehospital.cat.
Maria J ColominaDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Leo A Marin-CarceyDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Laura Viguera-FernandezDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Roser Bayona-DomengeDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Sara Garcia-BallesterDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Albert López-FarreDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Leticia Ruiz-BueraDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Maite Sanz-IturbeDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
David Álvarez-VillegasDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Ely C Jenssen-PazDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Guillermo Puig-SanzDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Aaron Arcos-TerronesDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Carmen Belmonte-CuencaDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Elia Perelada-AlonsoDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Francho Blasco-BlascoDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Antoni SabatéDepartment of Anaesthesiology and Critical Care, Bellvitge University Hospital, University of Barcelona, Hospitalet de Llobregat, carrer Feixa Llarga s/n, 08907, Barcelona, Spain.
Universitat de Barcelona · ESBellvitge University Hospital · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDuring the COVID-19 crisis it was necessary to generate a specific care network and reconvert operating rooms to attend emergency and high-acuity patients undergoing complex surgery. The aim of this study is to classify postoperative complications and mortality and to assess the impact that the COVID-19 pandemic may have had on the results.

methodsthis is a non-inferiority retrospective observational study. Two different groups of surgical patients were created: Pre-pandemic COVID and Pandemic COVID. Severity of illness was rated according to the Diagnosis-related Groups (DRG) score. Comparisons were made between groups and between DRG severity score-matched samples. Non-inferiority was set at up to 10 % difference for grade III to V complications according to the Clavien-Dindo classification, and up to 2 % difference in mortality.

resultsA total of 1649 patients in the PreCOVID group and 763 patients in the COVID group were analysed; 371 patients were matched for DRG severity score 3-4 (236 preCOVID and 135 COVID). No differences were found in relation to re-operation (22.5 % vs. 21.5 %) or late admission to critical care unit (5.1 % vs. 4.5 %). Clavien grade III to V complications occurred in 107 patients (45.3 %) in the PreCOVID group and in 56 patients (41.5 %) in the COVID group, and mortality was 12.7 % and 12.6 %, respectively. During the pandemic, 3 % of patients tested positive for Covid-19 on PCR: 12 patients undergoing elective surgery and 11 emergency surgery; there were 5 deaths, 3 of which were due to respiratory failure following Covid-19-induced pneumonia.

conclusionsAlthough this study has some limitations, it has shown the non-inferiority of surgical outcomes during the COVID pandemic, and indicates that resuming elective surgery is safe.

trial registrationClinicaltrials.gov identifier: NCT04780594 .

Indexed as

Surgical Procedures, OperativeAgedCausalityCOVID-19FemaleHumansMaleMiddle AgedPandemicsPatient AcuityPostoperative ComplicationsRetrospective StudiesRisk AssessmentSARS-CoV-2SpainClavien-Dindo complicationsElective surgeryEmergent surgeryMortalitySARS-CoV-2 (COVID19) pandemic

Identifiers

PMID34836504
PMCPMC8617361
OpenAlexW3215098031

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.