Evidence map›Paper›PMID 34836487›Full record

ArticleAutophagy2022

Post-transcriptional regulation of

Vikramjit Lahiri, Shree Padma Metur, Zehan Hu, Xinxin Song, Muriel Mari, Wayne D Hawkins, Janakraj Bhattarai, Elizabeth Delorme-Axford, Fulvio Reggiori, Daolin Tang and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in Autophagy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Autophagy in Inflammatory Response against SARS-CoV-2.International journal of molecular sciences · 2023
    Review
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Vikramjit LahiriLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Shree Padma MeturLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Zehan HuDepartment of Biology, University of Fribourg, Fribourg Switzerland.
Xinxin SongDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Muriel MariDepartment of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen The Netherlands.ORCID 0000-0002-2677-6945
Wayne D HawkinsLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
Janakraj BhattaraiDepartment of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.
Elizabeth Delorme-AxfordDepartment of Biological Sciences, Oakland University, Rochester, MI, USA.ORCID 0000-0002-7455-7616
Fulvio ReggioriDepartment of Biomedical Sciences of Cells and Systems, University of Groningen, University Medical Center Groningen, Groningen The Netherlands.ORCID 0000-0003-2652-2686
Daolin TangDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID 0000-0002-1903-6180
Joern DengjelDepartment of Biology, University of Fribourg, Fribourg Switzerland.ORCID 0000-0002-9453-4614
Daniel J KlionskyLife Sciences Institute, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0002-7828-8118
University of Michigan · USThe University of Texas Southwestern Medical Center · USUniversity Medical Center Groningen · NLUniversity of Fribourg · CHOakland University · US

Funding

The mechanism and regulation of autophagyR35GM131919 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DANIEL J. KLIONSKY · 2019 to 2026
$6.4M
Targeting HMGB1-mediated Autophagy in Cancer TherapyR01CA160417 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI TANG, DAOLIN · 2012 to 2023
$3.0M
NCI NIH HHS R01 CA160417NIGMS NIH HHS R35 GM131919
6 · The paper itself

Abstract

Macroautophagy/autophagy is a highly conserved nutrient-recycling pathway that eukaryotes utilize to combat diverse stresses including nutrient depletion. Dysregulation of autophagy disrupts cellular homeostasis leading to starvation susceptibility in yeast and disease development in humans. In yeast, the robust autophagy response to starvation is controlled by the upregulation of

Indexed as

Autophagy-Related Protein-1 HomologAutophagy-Related ProteinsProtein KinasesSaccharomyces cerevisiae ProteinsAutophagyCell Cycle ProteinsCheckpoint Kinase 2DEAD-box RNA HelicasesGene Expression Regulation, FungalNutrientsSaccharomyces cerevisiaeATG1 protein, S cerevisiaeAutophagy-Related Protein-1 HomologAutophagy-Related ProteinsCell Cycle ProteinsCheckpoint Kinase 2DEAD-box RNA HelicasesDED1 protein, S cerevisiaeNutrientsProtein KinasesRAD53 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsAmino acid starvationATG1autophagosomeautophagyDDX3DED1RAD53ULK1

Identifiers

PMID34836487
PMCPMC9298455
OpenAlexW3215403630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.