Evidence map›Paper›PMID 34836389›Full record

ArticleNutrients2021

Pronounced Trace Element Variation in Follicular Fluids of Subfertile Women Undergoing Assisted Reproduction.

Lilly Johanna Schmalbrock, Gregor Weiss, Eddy Rijntjes, Nina Reinschissler, Qian Sun, Michael Schenk, Lutz Schomburg

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Copper in Gynecological Diseases.International journal of molecular sciences · 2023
    Review
  8. Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Lilly Johanna SchmalbrockCardiovascular-Metabolic-Renal (CMR)-Research Center, Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hessische Straße 3-4, D-10115 Berlin, Germany.
Gregor WeissDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, A-8143 Dobl, Austria.ORCID 0000-0003-1045-8595
Eddy RijntjesCardiovascular-Metabolic-Renal (CMR)-Research Center, Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hessische Straße 3-4, D-10115 Berlin, Germany.
Nina ReinschisslerDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, A-8143 Dobl, Austria.
Qian SunCardiovascular-Metabolic-Renal (CMR)-Research Center, Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hessische Straße 3-4, D-10115 Berlin, Germany.ORCID 0000-0002-4458-6555
Michael SchenkDas Kinderwunsch Institut Schenk GmbH, Am Sendergrund 11, A-8143 Dobl, Austria.
Lutz SchomburgCardiovascular-Metabolic-Renal (CMR)-Research Center, Institut für Experimentelle Endokrinologie, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, Hessische Straße 3-4, D-10115 Berlin, Germany.ORCID 0000-0001-9445-1555
Humboldt-Universität zu Berlin · DE

Funding

Deutsche Forschungsgemeinschaft CRC/TR 296 "Local control of TH action" (LocoTact, P17)Deutsche Forschungsgemeinschaft research unit FOR-2558 "TraceAge" (Scho 849/6-2)
6 · The paper itself

Abstract

Female subfertility is a growing concern, especially in view of an increasing prevalence of polycystic ovary syndrome (PCOS). Assisted reproductive technologies (ART) offer a perspective for pregnancy, but the outcome rate is still suboptimal. The trace elements (TE), copper (Cu), selenium (Se), and zinc (Zn) are essential for fertility and development. We hypothesized that TE concentrations are related to oocyte quality and growth and affect pregnancy outcomes in women undergoing ART. Concentrations of TE were measured by total reflection X-ray fluorescence. Extracellular glutathione peroxidase 3 (GPX3) and selenoprotein P (SELENOP) were determined as additional Se biomarkers. Corresponding serum and follicular fluid (FF) samples were available from women with (

Indexed as

AdultBiomarkersCopperFemaleFollicular FluidGlutathione PeroxidaseHumansInfertility, FemaleOocytesPregnancyReproducibility of ResultsReproductive Techniques, AssistedSeleniumSelenoprotein PTrace ElementsZincBiomarkersCopperGlutathione PeroxidaseGPX3 protein, humanSeleniumSELENOP protein, humanSelenoprotein PTrace ElementsZincinfertilityPCOSseleniumtrace elements

Identifiers

PMID34836389
PMCPMC8619388
OpenAlexW3212887791

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.