Evidence map›Paper›PMID 34836380›Full record

ArticleNutrients2021

Increased Fat Taste Preference in Progranulin-Deficient Mice.

Lana Schumann, Annett Wilken-Schmitz, Sandra Trautmann, Alexandra Vogel, Yannick Schreiber, Lisa Hahnefeld, Robert Gurke, Gerd Geisslinger, Irmgard Tegeder

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lana SchumannInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Annett Wilken-SchmitzInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Sandra TrautmannInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Alexandra VogelInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Yannick SchreiberInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Lisa HahnefeldInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Robert GurkeInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Gerd GeisslingerInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.
Irmgard TegederInstitute of Clinical Pharmacology, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.ORCID 0000-0001-7524-8025
Goethe University Frankfurt · DE

Funding

Deutsche Forschungsgemeinschaft CRC1039 A03Deutsche Forschungsgemeinschaft CRC1039 Z01Deutsche Forschungsgemeinschaft CRC1080 C02Fraunhofer Cluster of Excellence for Immune Mediated diseases CIMD
6 · The paper itself

Abstract

Progranulin deficiency in mice is associated with deregulations of the scavenger receptor signaling of CD36/SCARB3 in immune disease models, and CD36 is a dominant receptor in taste bud cells in the tongue and contributes to the sensation of dietary fats. Progranulin-deficient mice (Grn

Indexed as

Dietary FatsWeight GainAnimalsCD36 AntigensFemaleFood PreferencesLipidsMaleMiceMice, Inbred C57BLMice, KnockoutMilkObesityProgranulinsReceptors, ScavengerTasteCD36 AntigensDietary FatsLipidsProgranulinsReceptors, ScavengerCD36IntelliCagelipidsprogranulintaste buds

Identifiers

PMID34836380
PMCPMC8623710
OpenAlexW3217586370

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.