Evidence map›Paper›PMID 34836319›Full record

ArticleNutrients2021

Adherence to a Mediterranean-Style Dietary Pattern and Cancer Risk in a Prospective Cohort Study.

Ioanna Yiannakou, Martha R Singer, Paul F Jacques, Vanessa Xanthakis, R Curtis Ellison, Lynn L Moore

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  4. Review
  5. Review
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  8. Article
  9. Effects of the Mediterranean diet polyphenols on cancer development.Journal of preventive medicine and hygiene · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ioanna YiannakouDepartment of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0003-4910-0013
Martha R SingerDepartment of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA.
Paul F JacquesNutritional Epidemiology, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111, USA.ORCID 0000-0001-5567-3147
Vanessa XanthakisDepartment of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA.
R Curtis EllisonDepartment of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA.
Lynn L MooreDepartment of Medicine, Preventive Medicine and Epidemiology, Boston University School of Medicine, Boston, MA 02118, USA.ORCID 0000-0002-1028-919X
Boston University · USTufts University · US

Funding

National Heart Lung and Blood Institute N01-HC-25195
6 · The paper itself

Abstract

A Mediterranean-style diet is a healthy eating pattern that may benefit cancer risk, but evidence among Americans is scarce. We examined the prospective association between adherence to such a diet pattern and total cancer risk. A Mediterranean-style dietary pattern (MSDP) score was derived from a semi-quantitative food frequency questionnaire at exam 5 (1991-1995). Subjects included 2966 participants of the Framingham Offspring Study who were free of prevalent cancer. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs), adjusting for demographic, lifestyle, and anthropometric measures. Cox-models were also used to examine effect modification by lifestyle and anthropometric measures. During 18 years of median follow-up, 259 women and 352 men were diagnosed with cancer. Women with moderate or higher adherence to the MSDP had ≥25% lower risks of cancer than women with the lowest MSDP (HR (moderate vs. lowest): 0.71, 95% CI: 0.52-0.97 and HR (highest vs. lowest): 0.74; 95% CI: 0.55-0.99). The association between MSDP score and cancer risk in men was weaker except in non-smokers. Beneficial effects of the MSDP in women were stronger among those who were not overweight. In this study, higher adherence to MSDP was associated with lower cancer risk, especially among women.

Indexed as

AdultAgedDiet, HealthyDiet, MediterraneanDiet SurveysExerciseFemaleGuideline AdherenceHumansLife StyleLongitudinal StudiesMaleMiddle AgedNeoplasmsNutrition PolicyPrevalencecancercohort studydiet patternsepidemiologyMediterranean diet

Identifiers

PMID34836319
PMCPMC8622098
OpenAlexW3214154401

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.