Evidence map›Paper›PMID 34836287›Full record

ReviewNutrients2021

Obesity, Sodium Homeostasis, and Arterial Hypertension in Children and Adolescents.

Małgorzata Wójcik, Agnieszka Kozioł-Kozakowska

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
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  8. ET-3/ETBR Mediates NaCirculation research · 2025
    Article
  9. Markers of Vascular Dysfunction in Hypertension.Current medicinal chemistry · 2025
    Review
  10. Article
  11. Review
  12. Article
  13. Review
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  15. Review
  16. Article
  17. Article
  18. Endothelial dysfunction as a factor leading to arterial hypertension.Pediatric nephrology (Berlin, Germany) · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Małgorzata WójcikDepartment of Pediatric and Adolescent Endocrinology, Chair of Pediatrics, Pediatric Institute, Jagiellonian University Medical College, 30-663 Kraków, Poland.ORCID 0000-0003-3889-1913
Agnieszka Kozioł-KozakowskaDepartment of Pediatrics, Gastroenterology and Nutrition, Institute of Pediatrics, Jagiellonian University Medical College, 30-663 Kraków, Poland.ORCID 0000-0003-4770-5641
Jagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between obesity, arterial hypertension, and excessive salt intake has been known for a long time; however, the mechanism of this relationship remains not clear.

methodsThe paper presents a current literature review on the relationship between salt consumption and the development of arterial hypertension in children and adolescents with obesity.

resultsIn addition to the traditional theory of hypertension development due to the increase in intravascular volume and disturbances of sodium excretion, recent studies indicate the existence of a complex mechanism related to excessive, pathological secretory activity of adipocytes, insulin resistance, and impaired function of the renin-angiotensin-aldosterone axis. That makes obese children and adolescents particularly vulnerable to the development of salt-sensitive arterial hypertension. Studies performed in many countries have shown that children and adolescents consume more sodium than recommended. It is worth noting, however, that the basis for these recommendations was the extrapolation of data from studies conducted on adults. Moreover, more important than sodium intake is the Na/K ratio and water consumption.

conclusionRegardless of the population-wide recommendations on reducing salt intake in children, specific recommendations for overweight and obese patients should be developed.

Indexed as

HomeostasisHypertensionPediatric ObesitySodium Chloride, DietaryAdolescentChildFeeding BehaviorHumansHyperinsulinismInsulin ResistanceMineralocorticoidsReceptors, MineralocorticoidSodiumMineralocorticoidsReceptors, MineralocorticoidSodiumSodium Chloride, Dietarychildrenhypertensionobesitysaltsodium

Identifiers

PMID34836287
PMCPMC8622119
OpenAlexW3212156637

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.