Evidence map›Paper›PMID 34836259›Full record

ArticleNutrients2021

Modified WCRF/AICR Score and All-Cause, Digestive System, Cardiovascular, Cancer and Other-Cause-Related Mortality: A Competing Risk Analysis of Two Cohort Studies Conducted in Southern Italy.

Antonella Mirizzi, Laura R Aballay, Giovanni Misciagna, Maria G Caruso, Caterina Bonfiglio, Paolo Sorino, Antonella Bianco, Angelo Campanella, Isabella Franco, Ritanna Curci and 5 more

Abstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Prognostic value of systemic inflammation-modified Patient-Generated Subjective Global Assessment in advanced cancers: A large-scale retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Antonella MirizziLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Laura R AballayHuman Nutrition Research Center (CenINH), School of Nutrition, Faculty of Medical Sciences, Universidad Nacional de Córdoba, Córdoba X5000, Argentina.ORCID 0000-0002-3430-3566
Giovanni MisciagnaScientific and Ethical Committee Polyclinic Hospital, University of Bari, 70124 Bari, Puglia, Italy.
Maria G CarusoScientific and Ethical Committee Polyclinic Hospital, University of Bari, 70124 Bari, Puglia, Italy.ORCID 0000-0003-4518-6307
Caterina BonfiglioLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.ORCID 0000-0002-8650-348X
Paolo SorinoLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.ORCID 0000-0002-9081-2648
Antonella BiancoLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Angelo CampanellaLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Isabella FrancoLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.ORCID 0000-0002-3697-0127
Ritanna CurciLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Filippo ProcinoLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Anna M CisterninoClinical Nutrition Outpatients Clinic, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Maria NotarnicolaLaboratory of Nutritional Biochemistry (MN), National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.ORCID 0000-0003-2274-2198
Pierina F D'AprileLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.
Alberto R OsellaLaboratory of Epidemiology and Biostatistics, National Gastroenterology Institute, "S. de Bellis" Research Hospital, Via Turi 27, 70013 Castellana Grotte, Bari, Italy.ORCID 0000-0003-4232-8760

Funding

Italian Ministry of Health ICS 160.2/RF 2003, 2004/2006Italian Ministry of Health Progetto no. 37-2004Italian Ministry of Health Ricerca Corrente DDG 045 del 24.01.2017Italian Ministry of Health Ricerca Corrente DDG 254 del 16.05.2012
6 · The paper itself

Abstract

backgroundIn real life, nutrition goes beyond purely biological domains. Primary prevention is the most efficient approach for reducing the risk of mortality. We aimed to study the association of lifestyle, as measured by a modified World Cancer Research Fund/American Institute for Cancer Research (mWCRF/AICR) scoring system with all-cause, digestive system disease-related (DSD-related), cardiovascular disease-related (CVD-related), cancer-related and other cause-related mortality using data from two population-based cohort studies conducted in Southern Italy.

methodsA random sample of 5271 subjects aged 18 years or older was enrolled in 2005-2006 and followed up until 2020. Usual food intakes were estimated using a validated dietary questionnaire. Competing risks survival models were applied.

resultsHigh adherence to the mWCRF/AICR score was found to be statistically significant and negatively associated with all-cause mortality (HR 0.56, 95%CI 0.39; 0.82), DSD-related mortality (SHR 0.38, 95%CI 0.15; 0.97) and cancer-related mortality (SHR 0.43, 95%CI 0.19; 0.97) in the male sub-cohort and other-cause mortality (SHR 0.43, 95%CI 0.21; 0.88) only in the female group.

conclusionsThis mWCRF/AICR score can be seen as a simple, easy tool for use in clinical practice to evaluate both qualitative and quantitative aspects of the diet.

Indexed as

Digestive SystemAdultAgedCardiovascular DiseasesCohort StudiesFemaleHumansItalyLife StyleMaleMiddle AgedNeoplasmsRisk AssessmentRisk FactorsSurveys and Questionnaireshigh adherencelifestyle scorerate of mortalitysub-distribution hazard ratio

Identifiers

PMID34836259
PMCPMC8620807

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.