ArticleNutrients2021
Diet Quality and Risk of Parkinson's Disease: The Rotterdam Study.
Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.
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The trial behind it
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Who cites it
26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Association between Mediterranean diet adherence and Parkinson's disease: a systematic review and meta-analysis.The journal of nutrition, health & aging · 2025Pooled it
- Adherence toFrontiers in nutrition · 2025Pooled it
- Effects of dietary supplements, foods, and dietary patterns in Parkinson's disease: meta-analysis and systematic review of randomized and crossover studies.European journal of clinical nutrition · 2024Pooled it
- Healthy Dietary Patterns and Risk of Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Environmental determinants of Parkinson's disease and attributable burden in Latin America.Research square · 2026Article
- Association Between Blood-Brain Barrier Disruption and Gut Microbiota Dysbiosis in Parkinson's Disease.Cellular and molecular neurobiology · 2026Review
- Association between food insecurity and Parkinson's disease: A cross-sectional analysis of nationally representative data.Medicine · 2026Article
- Adherence to the Mediterranean and Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) Diets and Parkinson's Disease Incidence in Women: Results from the Prospective E3N Cohort.Annals of neurology · 2026Article
- Bridging global diversity gaps in Parkinson disease research.Nature reviews. Neurology · 2026Review
- Gut microbiota and Parkinson's disease: exploring pathogenesis and potential therapeutic strategies from a gut-brain axis perspective.iScience · 2026Review
- The impact of diet on Parkinson's disease risk: A data-driven analysis in a large Italian case-control population.Journal of Parkinson's disease · 2026Article
- Dietary habits and adherence to the Mediterranean diet in a cohort of Parkinson's disease patients in Lithuania.Frontiers in nutrition · 2026Article
- Mediterranean Diet, Polyphenols, and Neuroprotection: Mechanistic Insights into Resveratrol and Oleuropein.Nutrients · 2025Review
- Exploring the Facilitators and Barriers of Adherence to Mediterranean-Ketogenic Dietary Interventions in Parkinson's Disease: A Qualitative Study.Current developments in nutrition · 2025Article
- Mediterranean dietary pattern and risk of neurodegenerative diseases in a cohort of Swedish women.NPJ Parkinson's disease · 2025Article
- A Narrative Review on Biochemical Markers and Emerging Treatments in Prodromal Synucleinopathies.Clinics and practice · 2025Review
- Modifiable risk factors associated with the risk of developing Parkinson's disease: a critical review.Arquivos de neuro-psiquiatria · 2025Review
- The Role of Diet in Parkinson's Disease.Journal of Parkinson's disease · 2024Review
- What Dietary Vitamins and Minerals Might Be Protective against Parkinson's Disease?Brain sciences · 2023Article
- Mediterranean Diet and Melatonin: A Systematic Review.Antioxidants (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
The Mediterranean diet has been associated with the risk of Parkinson's disease (PD), but limited research has been performed on other dietary patterns. We studied the relationship between overall diet quality and PD risk in the general population. We included 9414 participants from the Rotterdam Study, a prospective population-based study in the Netherlands. Diet was defined using a Dutch diet quality score, a Mediterranean diet score and data-driven dietary patterns constructed with principal component analysis (PCA). During an average follow-up of 14.1 years, PD was diagnosed in 129 participants. We identified a 'Prudent', 'Unhealthy' and 'Traditional Dutch' pattern from the PCA. We found a possible association between the Mediterranean diet (Hazard ratio (HR) per standard deviation (SD) 0.89 (95% confidence interval (CI) 0.74-1.07)), the 'Prudent' pattern (HR per SD 0.81 (95% CI 0.61-1.08)) and the risk of PD. However, no associations with PD risk were found for the Dutch diet quality score (HR per SD 0.93 (95% CI 0.77-1.12)), the 'Unhealthy' pattern (HR per SD 1.05 (95% CI 0.85-1.29)) or the 'Traditional Dutch' pattern (HR per SD 0.90 (95% CI 0.69-1.17)). In conclusion, our results corroborate previous findings of a possible protective effect of the Mediterranean diet. Further research is warranted to study the effect of other dietary patterns on PD risk.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.