Evidence map›Paper›PMID 34836219›Full record

Observational studyNutrients2021

Long-Term Evolution of Malnutrition and Loss of Muscle Strength after COVID-19: A Major and Neglected Component of Long COVID-19.

Marine Gérard, Meliha Mahmutovic, Aurélie Malgras, Niasha Michot, Nicolas Scheyer, Roland Jaussaud, Phi-Linh Nguyen-Thi, Didier Quilliot

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.

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  17. Malnutrition in COVID-19 survivors: prevalence and risk factors.Aging clinical and experimental research · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Marine GérardTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.
Meliha MahmutovicTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.
Aurélie MalgrasTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.
Niasha MichotTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.ORCID 0000-0002-0538-1581
Nicolas ScheyerTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.
Roland JaussaudInternal Medicine and Clinical Immunology Department, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.
Phi-Linh Nguyen-ThiMedical Evaluation Department, Department of Clinical Research Support PARC, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.ORCID 0000-0002-1369-6081
Didier QuilliotTransversal Nutrition Unit, University of Lorraine, Nancy University Hospital, 54500 Vandoeuvre-les-Nancy, France.ORCID 0000-0001-8143-9856
Université de Lorraine · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-acute consequences of COVID-19, also termed long COVID, include signs and symptoms persisting for more than 12 weeks with prolonged multisystem involvement; most often, however, malnutrition is ignored.

methodThe objective was to analyze persistent symptoms, nutritional status, the evolution of muscle strength and performance status (PS) at 6 months post-discharge in a cohort of COVID-19 survivors.

resultsOf 549 consecutive patients hospitalized for COVID-19 between 1 March and 29 April 2020, 23.7% died and 288 patients were at home at D30 post-discharge. At this date, 136 of them (47.2%) presented persistent malnutrition, a significant decrease in muscle strength or a PS ≥ 2. These patients received dietary counseling, nutritional supplementation, adapted physical activity guidance or physiotherapy assistance, or were admitted to post-care facilities. At 6 months post-discharge, 91.0% of the 136 patients (n = 119) were evaluated and 36.0% had persistent malnutrition, 14.3% complained of a significant decrease in muscle strength and 14.9% had a performance status > 2. Obesity was more frequent in patients with impairment than in those without (52.8% vs. 31.0%;

conclusionsObese subjects as well as patients who have stayed in intensive care have a higher risk of functional loss or undernutrition 6 months after a severe COVID infection. Malnutrition and loss of muscle strength should be considered in the clinical assessment of these patients.

Indexed as

Muscle StrengthNutritional StatusAdultAgedCOVID-19FemaleFunctional StatusHospitalizationHumansLength of StayMaleMalnutritionMiddle AgedMuscle, SkeletalMuscle WeaknessObesitycohort studyintensive care unitlong COVID-19malnutritionmuscle strengthobesityperformance statusself-evaluation

Identifiers

PMID34836219
PMCPMC8618979
OpenAlexW3213373966

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.