Evidence map›Paper›PMID 34836201›Full record

ArticleNutrients2021

One Year Follow-Up of Taste-Related Reward Associations with Weight Loss Suggests a Critical Time to Mitigate Weight Regain Following Bariatric Surgery.

Kimberly R Smith, Anahys Aghababian, Afroditi Papantoni, Maria G Veldhuizen, Vidyulata Kamath, Civonnia Harris, Timothy H Moran, Susan Carnell, Kimberley E Steele

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Kimberly R SmithDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-7414-9164
Anahys AghababianDivision of Child and Adolescent Psychiatry, Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Afroditi PapantoniDivision of Child and Adolescent Psychiatry, Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.ORCID 0000-0001-6539-095X
Maria G VeldhuizenAnatomy Department, Mersin University School of Medicine, 32133 Mersin, Turkey.ORCID 0000-0001-8375-7719
Vidyulata KamathDivision of Medical Psychology, Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Civonnia HarrisJohns Hopkins Center for Bariatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Timothy H MoranDepartment of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Susan CarnellDivision of Child and Adolescent Psychiatry, Department of Psychiatry & Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Kimberley E SteeleJohns Hopkins Center for Bariatric Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
Johns Hopkins University · USMersin Üniversitesi · TR

Funding

Neurobiologic Alterations in Bariatric Surgery: Taste Response and Weight LossK23DK100559 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI STEELE, KIMBERLEY EDEN · 2014 to 2017
$709k
Dalio Philanthropies n/aNIH HHS K23DK100559
6 · The paper itself

Abstract

backgroundWeight regain is a concerning issue in bariatric patients. We previously demonstrated that taste-related reward processing was associated with six-month weight loss outcomes following Roux-en-Y gastric bypass (RYGB) but not vertical sleeve gastrectomy (VSG). Here, we assessed whether these taste factors persisted in predicting weight loss, and weight regain, at one year post-surgery.

methodsAdult women enrolled in a longitudinal study of taste preferences following bariatric surgery completed behavioral and neuroimaging assessments at one year post-surgery.

resultsRYGB produced better weight loss relative to VSG, with weight regain and greater weight loss variability observed from six months to one year post-VSG. Changes in liking for high fat at 2 weeks post-surgery from baseline remained a predictor of weight loss in RYGB, but other predictors did not persist. Average liking ratings rebounded to baseline and higher self-reported food cravings and dietary disinhibition correlated with poorer weight loss at one year post-surgery.

conclusionInitial anatomical and metabolic changes resulting from RYGB that reset neural processing of reward stimuli in the mesolimbic pathway appear to be temporary and may be contingent upon post-operative eating behaviors returning to preoperative obesogenic tendencies. Six months post-surgery may be a critical window for implementing interventions to mitigate weight gain.

Indexed as

RewardTasteWeight LossAdolescentAdultFeeding BehaviorFemaleFollow-Up StudiesGastric BypassHumansLongitudinal StudiesMiddle AgedObesity, MorbidPostoperative PeriodTime FactorsWeight Gainbariatric surgeryrewardRoux-en-Y gastric bypasstastevertical sleeve gastrectomyweight loss

Identifiers

PMID34836201
PMCPMC8623884
OpenAlexW3213102631

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.