Evidence map›Paper›PMID 34836158›Full record

ArticleNutrients2021

Low-Carbohydrate Diet among Children with Type 1 Diabetes: A Multi-Center Study.

Vit Neuman, Lukas Plachy, Stepanka Pruhova, Stanislava Kolouskova, Lenka Petruzelkova, Barbora Obermannova, Jana Vyzralkova, Petra Konecna, Jan Vosahlo, Martina Romanova and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Observational
  6. Prolonging Partial Remission in Type 1 Diabetes: The Role of Low-Carbohydrate Diet: A Literature Review.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026
    Review
  7. Article
  8. Review
  9. Severe growth retardation during carbohydrate restriction in type 1 diabetes mellitus: A case report.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2024
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Vit NeumanDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.ORCID 0000-0002-1745-5285
Lukas PlachyDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.
Stepanka PruhovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.
Stanislava KolouskovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.
Lenka PetruzelkovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.
Barbora ObermannovaDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.
Jana VyzralkovaDepartment of Pediatrics, University Hospital Brno, CZ-62500 Brno, Czech Republic.
Petra KonecnaDepartment of Pediatrics, University Hospital Brno, CZ-62500 Brno, Czech Republic.
Jan VosahloDepartment of Pediatrics, 3rd Faculty of Medicine, Charles University and Kralovske Vinohrady University Hospital, CZ-10034 Prague, Czech Republic.
Martina RomanovaDepartment of Pediatrics, 3rd Faculty of Medicine, Charles University and Kralovske Vinohrady University Hospital, CZ-10034 Prague, Czech Republic.
Marketa PavlikovaDepartment of Probability and Mathematical Statistics, Faculty of Mathematics and Physics, Charles University, CZ-18675 Prague, Czech Republic.
Zdenek SumnikDepartment of Pediatrics, 2nd Faculty of Medicine, Charles University and Motol University Hospital, CZ-15006 Prague, Czech Republic.ORCID 0000-0002-6462-6462
Charles University · CZUniversity Hospital Brno · CZ

Funding

Ministry of Health of the Czech Republic AZV grant NU21-01-00085
6 · The paper itself

Abstract

aims/hypothesisThe proportion of children with type 1 diabetes (T1D) who have experience with low-carbohydrate diet (LCD) is unknown. Our goal was to map the frequency of LCD among children with T1D and to describe their clinical and laboratory data.

methodsCaregivers of 1040 children with T1D from three centers were addressed with a structured questionnaire regarding the children's carbohydrate intake and experience with LCD (daily energy intake from carbohydrates below 26% of age-recommended values). The subjects currently on LCD were compared to a group of non-LCD respondents matched to age, T1D duration, sex, type and center of treatment.

resultsA total of 624/1040 (60%) of the subjects completed the survey. A total of 242/624 (39%) subjects reported experience with voluntary carbohydrate restriction with 36/624 (5.8%) subjects currently following the LCD. The LCD group had similar HbA1c (45 vs. 49.5, CONCLUSIONS/

interpretationLow carbohydrate diet is not scarce in children with T1D and is associated with modestly better disease control. At the same time, caution should be applied as it showed a tendency toward more frequent hypoglycemia.

Indexed as

Diet, Carbohydrate-RestrictedBlood GlucoseBody HeightBody Mass IndexBody WeightChildDiabetes Mellitus, Type 1FemaleGlycated HemoglobinHumansLipidsMaleSurveys and QuestionnairesBlood GlucoseGlycated HemoglobinLipidslow-carbohydrate diettime in rangetype 1 diabetes

Identifiers

PMID34836158
PMCPMC8622801
OpenAlexW3211226558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.