Evidence map›Paper›PMID 34836151›Full record

ArticleNutrients2021

Water Kefir and Derived Pasteurized Beverages Modulate Gut Microbiota, Intestinal Permeability and Cytokine Production In Vitro.

Marta Calatayud, Rosa Aragao Börner, Jonas Ghyselinck, Lynn Verstrepen, Jelle De Medts, Pieter Van den Abbeele, Claire L Boulangé, Sarah Priour, Massimo Marzorati, Sami Damak

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Marta CalatayudProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Rosa Aragao BörnerNestlé Institute of Health Sciences, and Nestlé Institute of Material Sciences, Nestlé Research, Société des Produits Nestlé S.A., Vers-chez-les-Blanc, 1000 Lausanne, Switzerland.ORCID 0000-0003-1458-3692
Jonas GhyselinckProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Lynn VerstrepenProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Jelle De MedtsProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Pieter Van den AbbeeleProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Claire L BoulangéNestlé Institute of Health Sciences, and Nestlé Institute of Material Sciences, Nestlé Research, Société des Produits Nestlé S.A., Vers-chez-les-Blanc, 1000 Lausanne, Switzerland.
Sarah PriourNestlé Institute of Health Sciences, and Nestlé Institute of Material Sciences, Nestlé Research, Société des Produits Nestlé S.A., Vers-chez-les-Blanc, 1000 Lausanne, Switzerland.
Massimo MarzoratiProDigest, Technologiepark 82, 9052 Zwijnaarde, Belgium.
Sami DamakNestlé Institute of Health Sciences, and Nestlé Institute of Material Sciences, Nestlé Research, Société des Produits Nestlé S.A., Vers-chez-les-Blanc, 1000 Lausanne, Switzerland.
Nestlé (Switzerland) · CHProDigest (Belgium) · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fermentation is an ancient food preservation process, and fermented products have been traditionally consumed in different cultures worldwide over the years. The interplay between human gut microbiota, diet and host health is widely recognized. Diet is one of the main factors modulating gut microbiota potentially with beneficial effects on human health. Fermented dairy products have received much attention, but other sources of probiotic delivery through food received far less attention. In this research, a combination of in vitro tools mimicking colonic fermentation and the intestinal epithelium have been applied to study the effect of different pasteurized and non-pasteurized water kefir products on gut microbiota, epithelial barrier function and immunomodulation. Water kefir increased beneficial short-chain fatty acid production at the microbial level, reduced detrimental proteolytic fermentation compounds and increased

Indexed as

Gastrointestinal MicrobiomeKefirBeveragesColonCytokinesFatty Acids, VolatileFermentationHumansIntestinal MucosaPasteurizationPermeabilityWaterCytokinesFatty Acids, VolatileWatergut barrierimmunomodulationmicrobiotashort-chain fatty acidswater kefir

Identifiers

PMID34836151
PMCPMC8625349
OpenAlexW3210229972

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.