Evidence map›Paper›PMID 34836081›Full record

Trial reportNutrients2021

The Effect of Weight-Loss Interventions on Cervical and Chin Subcutaneous Fat Depots; the CENTRAL Randomized Controlled Trial.

Gal Tsaban, Avital Bilitzky-Kopit, Anat Yaskolka Meir, Hila Zelicha, Yftach Gepner, Ilan Shelef, Omri Orr, Yoash Chassidim, Benjamin Sarusi, Uta Ceglarek and 5 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 7 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 3 countries.

Gal TsabanFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.ORCID 0000-0003-4234-6504
Avital Bilitzky-KopitFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Anat Yaskolka MeirFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.ORCID 0000-0002-2480-3751
Hila ZelichaFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Yftach GepnerDepartment of Epidemiology and Preventive Medicine, Sackler Faculty of Medicine, and Sylvan Adams Sports Institute, School of Public Health, Tel-Aviv University, Tel-Aviv 96678, Israel.ORCID 0000-0002-3128-3539
Ilan ShelefDivision of Clinical Radiology, Soroka University Medical Center, Beer-Sheva 84101, Israel.ORCID 0000-0002-8398-6455
Omri OrrFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.
Yoash ChassidimResearch Center, Soroka University Medical Center, Beer-Sheva 84101, Israel.
Benjamin SarusiDepartment of Medicine, Nuclear Research Center Negev, Dimona 84190, Israel.
Uta CeglarekDepartment of Medicine, University of Leipzig, 04103 Leipzig, Germany.
Michael StumvollDepartment of Medicine, University of Leipzig, 04103 Leipzig, Germany.
Matthias BlüherDepartment of Medicine, University of Leipzig, 04103 Leipzig, Germany.ORCID 0000-0003-0208-2065
Meir J StampferChanning Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Iris ShaiFaculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 84105, Israel.ORCID 0000-0001-9050-4605
Dan SchwarzfuchsDepartment of Medicine, Nuclear Research Center Negev, Dimona 84190, Israel.
Ben-Gurion University of the Negev · ILLeipzig University · DESoroka Medical Center · ILBrigham and Women's Hospital · USTel Aviv University · IL

Funding

CSRD VA 1Deutsche Forschungsgemeinschaft SFB1052Israel Ministry of Science and Technology 3-13604
6 · The paper itself

Abstract

Accumulation of cervical and chin subcutaneous adipose tissues (SAT) represent known phenotypes of obesity. We aimed to evaluate the sensitivity of these fat storages to long-term weight-loss directed lifestyle-intervention and to assess their relations to bodily-adiposity, insulin-resistance, and cardiometabolic risk; We randomly assigned 278 participants with abdominal-obesity/dyslipidemia to low-fat or Mediterranean/low-carbohydrate diets +/- physical-activity. All participants underwent an 18 month whole-body magnetic resonance imaging follow-up, from which we assessed cervical and chin SAT-areas; Participants (age = 48 years; 90% men; body-mass-index = 30.9 kg/m

Indexed as

AdiposityAdultBody CompositionBody Mass IndexChinCholesterol, HDLDyslipidemiasFemaleHumansInsulin ResistanceMagnetic Resonance ImagingMaleMiddle AgedNeckObesitySubcutaneous FatCholesterol, HDLTriglyceridescervical subcutaneous fatchin subcutaneous fatdietary interventioninsulin resistancemagnetic resonance imagingweight loss

Identifiers

PMID34836081
PMCPMC8617936
OpenAlexW3208373620

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.