Evidence map›Paper›PMID 34836009›Full record

Trial reportNutrients2021

Randomized Controlled Trial for Promotion of Healthy Eating in Older Adults by Increasing Consumption of Plant-Based Foods: Effect on Inflammatory Biomarkers.

Andreas Nilsson, Antonio Cano, Oscar Bergens, Fawzi Kadi

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07728877 (A Culture-tailored Plant-based Dietary Intervention in Taiwan), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07728877 nacompletednot on this mapstarted 2023, after this paper: background citation

A Culture-tailored Plant-based Dietary Intervention in Taiwan: A Pilot Randomized Crossover Feasibility Trial With Preliminary Inflammatory and Metabolic Outcomes

TypeinterventionalSponsorTzu Chi UniversityRan2023 to 2023Enrolled30ConditionsHealthy, Dietary HabitsArmsPlant-Based Diet, General Diet
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Andreas NilssonSchool of Health Sciences, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0003-3793-335X
Antonio CanoService of Obstetrics and Gynecology, Hospital Clínico Universitario-INCLIVA, 46010 Valencia, Spain.ORCID 0000-0001-8046-0303
Oscar BergensSchool of Health Sciences, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0002-1767-9297
Fawzi KadiSchool of Health Sciences, Örebro University, 701 82 Örebro, Sweden.ORCID 0000-0002-9831-0896
Örebro University · SEUniversitat de València · ES

Funding

EU HORIZON 2020 Research and Innovation Programme 727565
6 · The paper itself

Abstract

To what extent the intake of fruit and vegetables (FV) influences inflammatory status remains elusive, particularly in older populations. The aim of the present study was to determine the effect of increased FV intake for 16 weeks on circulating biomarkers of inflammation in a population of older men and women. Sixty-six participants (65-70 years) randomly assigned to either FV or control (CON) groups were instructed to increase FV intake to five servings per day through nutritional counseling (FV) or to maintain habitual diet (CON). Dietary intake and physical activity level (PA) were determined using food frequency questionnaire and accelerometers, respectively, at the start and end of the intervention. C-reactive protein (CRP), interleukin 6 (IL-6), IL-18, macrophage inflammatory protein-1α (MIP-1α), MIP-1β, tumor necrosis factor-α (TNF-α), TNF-related apoptosis-inducing ligand (TRAIL), TNF-related activation-induced cytokine (TRANCE), and C-X3-C motif chemokine ligand-1 (CX3CL1, or fractalkine) were analyzed. The FV group significantly increased daily FV intake (from 2.2 ± 1.3 to 4.2 ± 1.8 servings/day), with no change in CON. Waist circumference and PA level were unchanged by the intervention. Interaction effects (time × group,

Indexed as

FruitVegetablesAccelerometryAgedBiomarkersC-Reactive ProteinCytokinesDiet, HealthyDiet, VegetarianEatingElder Nutritional Physiological PhenomenaExerciseFeeding BehaviorFemaleHealth PromotionHumansBiomarkersC-Reactive ProteinCytokinesInflammation MediatorsagingCX3CL1dietfruit and vegetablesinflammationnutritionphysical activityTRAILTRANCE

Identifiers

PMID34836009
PMCPMC8623008
OpenAlexW3208933193

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.