Evidence map›Paper›PMID 34835990›Full record

ReviewNutrients2021

Role of CD38 in Adipose Tissue: Tuning Coenzyme Availability?

Andrea Benzi, Alessia Grozio, Sonia Spinelli, Laura Sturla, Andreas H Guse, Antonio De Flora, Elena Zocchi, Joerg Heeren, Santina Bruzzone

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Inhibition of CD38 by 78c Enhanced NADInternational journal of molecular sciences · 2026
    Article
  2. Article
  3. Inhibition of CD38 by 78c Enhanced NADInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Andrea BenziDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.
Alessia GrozioBuck Institute for Research on Aging, Novato, CA 94945, USA.ORCID 0000-0003-4699-3303
Sonia SpinelliDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.ORCID 0000-0001-9847-4308
Laura SturlaDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.ORCID 0000-0002-3976-5874
Andreas H GuseDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.
Antonio De FloraDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.
Elena ZocchiDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.
Joerg HeerenDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany.ORCID 0000-0002-5647-1034
Santina BruzzoneDIMES-Section of Biochemistry, University of Genova, 16132 Genova, Italy.ORCID 0000-0003-2034-3716
University of Genoa · ITUniversität Hamburg · DEBuck Institute for Research on Aging · US

Funding

Deutsche Forschungsgemeinschaft project-ID: 335447727Deutsche Forschungsgemeinschaft SFB 1328German Academic Exchange Service Faculty Research Visit GrantMinistry of Education, Universities and Research PRIN 2017Z5LR5Z_003
6 · The paper itself

Abstract

Nicotinamide adenine dinucleotide (NAD

Indexed as

Adipose TissueADP-ribosyl Cyclase 1AnimalsCoenzymesHumansModels, BiologicalNADThermogenesisADP-ribosyl Cyclase 1CoenzymesNADadipose tissueCD38nicotinamide adenine dinucleotide

Identifiers

PMID34835990
PMCPMC8624254
OpenAlexW3208260733

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.