Evidence map›Paper›PMID 34835987›Full record

Trial reportNutrients2021

Psychophysiological Effects of

Hui-Mei Chen, Po-Hsiu Kuo, Chia-Yueh Hsu, Yi-Hung Chiu, Yen-Wenn Liu, Mong-Liang Lu, Chun-Hsin Chen

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 6 pooled it
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 6 syntheses or guidelines pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Probiotics for the treatment of depression and its comorbidities: A systemic review.Frontiers in cellular and infection microbiology · 2023
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Efficacy ofInternational journal of molecular sciences · 2025
    Article
  13. Review
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  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Frontiers in nutrition · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hui-Mei ChenInstitute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei 100, Taiwan.
Po-Hsiu KuoInstitute of Epidemiology and Preventive Medicine, National Taiwan University, Taipei 100, Taiwan.ORCID 0000-0003-0365-3587
Chia-Yueh HsuDepartment of Psychiatry, Taipei Municipal Wan-Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Yi-Hung ChiuDepartment of Psychiatry, Taipei Municipal Wan-Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Yen-Wenn LiuInstitute of Biochemistry of Molecular Biology, National Yang-Ming University, Taipei 112, Taiwan.
Mong-Liang LuDepartment of Psychiatry, Taipei Municipal Wan-Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Chun-Hsin ChenDepartment of Psychiatry, Taipei Municipal Wan-Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Wan Fang Hospital · TWNational Taiwan University · TWNational Yang Ming Chiao Tung University · TW

Funding

Ministry of Science and Technology, Taipei, Taiwan 109-2314-B-038-084; 108-2314-B-038-077; 107-2314-B-038-085Taipei Medical University IIT-107-2
6 · The paper itself

Abstract

Recent studies have suggested that gut-brain axis may be one of the mechanisms of major depression disorder (MDD). The current study aimed to investigate the effects of

Indexed as

AdultAgedBiodiversityBiomarkersGastrointestinal MicrobiomeHumansLactiplantibacillus plantarumMajor Depressive DisorderMiddle AgedPhylogenyPsychophysiologySurveys and QuestionnairesYoung AdultBiomarkersgut permeabilityinflammationmajor depressive disordermicrobiotaprobiotics

Identifiers

PMID34835987
PMCPMC8618644
OpenAlexW3208061771

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.