Evidence map›Paper›PMID 34835980›Full record

ArticleNutrients2021

Human Milk Lactose, Insulin, and Glucose Relative to Infant Body Composition during Exclusive Breastfeeding.

Ali S Cheema, Lisa F Stinson, Alethea Rea, Ching Tat Lai, Matthew S Payne, Kevin Murray, Donna T Geddes, Zoya Gridneva

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07457515 (Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet), which is not on this map. Cited by 25 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07457515 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Analysis of the Transmission of Overweight/Obesity in the Mother-breastmilk-child Triad in Relation to Maternal Cardiometabolic Status and Diet

TypeobservationalSponsorWarsaw University of Life SciencesRan2026 to 2029Enrolled165ConditionsBody Weight, Obesity & Overweight, Human Milk/Breastfeeding, Body Composition
3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ali S CheemaSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0002-3481-5254
Lisa F StinsonSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Alethea ReaMathematics and Statistics, Murdoch University, Murdoch, WA 6150, Australia.
Ching Tat LaiSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0002-9025-4922
Matthew S PayneDivision of Obstetrics and Gynaecology, UWA Medical School, The University of Western Australia, Crawley, WA 6009, Australia.
Kevin MurraySchool of Population and Global Health, The University of Western Australia, Crawley, WA 6009, Australia.
Donna T GeddesSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.
Zoya GridnevaSchool of Molecular Sciences, The University of Western Australia, Crawley, WA 6009, Australia.ORCID 0000-0001-6841-2958
The University of Western Australia · AUMurdoch University · AU

Funding

Medela AG The University of Western AustraliaUniversity of Western Australia Scholarships for International Research Fees
6 · The paper itself

Abstract

Human milk (HM) components may influence infant growth and development. This study aimed to investigate relationships between infant body composition (BC) and HM lactose, insulin, and glucose (concentrations and calculated daily intakes (CDI)) as well as 24-h milk intake and maternal BC at 3 months postpartum. HM samples were collected at 2 months postpartum. Infant and maternal BC was assessed with bioimpedance spectroscopy. Statistical analysis used linear regression accounting for infant birth weight. 24-h milk intake and CDI of lactose were positively associated with infant anthropometry, lean body mass and adiposity. Higher maternal BC measures were associated with lower infant anthropometry, z-scores, lean body mass, and adiposity. Maternal characteristics including BC and age were associated with concentrations and CDI of HM components, and 24-h milk intake. In conclusion, 24-h intake of HM and lactose as well as maternal adiposity are related to development of infant BC.

Indexed as

Breast FeedingAdultBody CompositionFemaleGlucoseHumansInfant, NewbornInsulinLactoseMaleMiddle AgedMilk, HumanPostpartum PeriodGlucoseInsulinLactosebioelectrical impedance spectroscopybody compositionbreastfeedingglucosehuman milkinfantinsulinintakelactationlactose

Identifiers

PMID34835980
PMCPMC8625960
OpenAlexW3208241041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.