Evidence map›Paper›PMID 34835954›Full record

Trial reportNutrients2021

Randomized Controlled Trial of Probiotic PS128 in Children with Tourette Syndrome.

Chang-Chun Wu, Lee-Chin Wong, Chia-Jui Hsu, Chianne-Wen Yang, Ying-Chieh Tsai, Feng-Shiang Cheng, Hsiao-Yun Hu, Wang-Tso Lee

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 6 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 6 syntheses or guidelines pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Chang-Chun WuDepartment of Pediatric Neurology, National Taiwan University Children's Hospital, Taipei 100, Taiwan.
Lee-Chin WongDepartment of Pediatric Neurology, National Taiwan University Children's Hospital, Taipei 100, Taiwan.
Chia-Jui HsuDepartment of Pediatrics, National Taiwan University Hospital Hsin-Chu Branch, Hsin-Chu 300, Taiwan.
Chianne-Wen YangDepartment of Pediatric Neurology, National Taiwan University Children's Hospital, Taipei 100, Taiwan.
Ying-Chieh TsaiInstitute of Biochemistry and Molecular Biology, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.ORCID 0000-0002-4390-4742
Feng-Shiang ChengDepartment of Education and Research, Taipei City Hospital, Taipei 106, Taiwan.
Hsiao-Yun HuDepartment of Education and Research, Taipei City Hospital, Taipei 106, Taiwan.ORCID 0000-0003-3604-3494
Wang-Tso LeeDepartment of Pediatric Neurology, National Taiwan University Children's Hospital, Taipei 100, Taiwan.
National Yang Ming Chiao Tung University · TWNational Taiwan University Hospital · TWCathay General Hospital · TWNational Taiwan University · TWTaipei City Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tourette syndrome results from a complex interaction between social-environmental factors, multiple genetic abnormalities, and neurotransmitter disturbances. This study is a double-blinded, randomized controlled trial using probiotics

Indexed as

ChildComorbidityFemaleFollow-Up StudiesHumansMaleObsessive-Compulsive DisorderOutcome Assessment, Health CarePlacebosProbioticsSurveys and QuestionnairesTourette SyndromePlacebosattention deficit hyperactivity disorderchildrenprobiotics PS128ticsTourette syndrome

Identifiers

PMID34835954
PMCPMC8619307
OpenAlexW3205692302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.