Evidence map›Paper›PMID 34835918›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Anticancer Potential of L-Histidine-Capped Silver Nanoparticles against Human Cervical Cancer Cells (SiHA).

Rajmohamed Mohammed Asik, Chidhambaram Manikkaraja, Karuppusamy Tamil Surya, Natarajan Suganthy, Archunan Priya Aarthy, Domokos Mathe, Muthusamy Sivakumar, Govindaraju Archunan, Parasuraman Padmanabhan, Balazs Gulyas

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Short Fragmented Peptides fromCurrent drug discovery technologies · 2024
    Article
  5. Review
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Rajmohamed Mohammed AsikDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.ORCID 0000-0002-6327-0134
Chidhambaram ManikkarajaDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.ORCID 0000-0002-3901-4456
Karuppusamy Tamil SuryaDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.
Natarajan SuganthyDepartment of Nanoscience and Technology, Alagappa University, Karaikudi 630003, India.ORCID 0000-0002-1273-8497
Archunan Priya AarthyDepartment of Obstetrics and Gynecology, Rabindra Nath Tagore Medical College, Udaipur 313001, India.
Domokos MatheDepartment of Biophysics and Radiation Biology, Semmelweis University, 1094 Budapest, Hungary.
Muthusamy SivakumarAriviya Technologies Pvt Ltd., Pattukkottai, Thanjavur 614602, India.ORCID 0000-0001-9070-5570
Govindaraju ArchunanDepartment of Animal Science, Bharathidasan University, Tiruchirappalli 620024, India.
Parasuraman PadmanabhanLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.ORCID 0000-0003-4112-4600
Balazs GulyasLee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study reports the synthesis of silver nanoparticles using amino acid L-histidine as a reducing and capping agent as an eco-friendly approach. Fabricated L-histidine-capped silver nanoparticles (L-HAgNPs) were characterized by spectroscopic and microscopic studies. Spherical shaped L-HAgNPs were synthesized with a particle size of 47.43 ± 19.83 nm and zeta potential of -20.5 ± 0.95 mV. Results of the anticancer potential of L-HAgNPs showed antiproliferative effect against SiHa cells in a dose-dependent manner with an IC

Indexed as

anticancer activityapoptosiscervical cancer cellsL-histidinesilver nanoparticles

Identifiers

PMID34835918
PMCPMC8618575

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.