Evidence map›Paper›PMID 34835916›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Ciprofloxacin-Loaded Gold Nanoparticles against Antimicrobial Resistance: An In Vivo Assessment.

Afrah Nawaz, Syed Mohsin Ali, Nosheen Fatima Rana, Tahreem Tanweer, Amna Batool, Thomas J Webster, Farid Menaa, Sundus Riaz, Zahra Rehman, Farhat Batool and 5 more

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 63 citations in OpenAlex.

  1. Review
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  6. Article
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  8. Review
  9. Phytogenic nanoparticles: synthesis, characterization, and their roles in physiology and biochemistry of plants.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2024
    Review
  10. Review
  11. Article
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  15. Article
  16. Article
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  18. Recent Advances in Antimicrobial Nano-Drug Delivery Systems.Nanomaterials (Basel, Switzerland) · 2022
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 2 institutions in 1 country.

Afrah NawazDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Syed Mohsin AliDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Nosheen Fatima RanaDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Tahreem TanweerDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.ORCID 0000-0001-6807-0054
Amna BatoolDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Thomas J WebsterDepartment of Chemical Engineering, Northeastern University, Boston, MA 02115, USA.ORCID 0000-0002-2028-5969
Farid MenaaDepartments of Internal Medicine and Nanomedicine, California Innovations Corporation, San Diego, CA 92037, USA.ORCID 0000-0002-0258-7322
Sundus RiazDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Zahra RehmanDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Farhat BatoolDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Misha FatimaDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Tuba MaryamDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Iqra ShafiqueDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Abida SaleemDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.
Arfa IqbalDepartment of Biomedical Engineering and Sciences, School of Mechanical & Manufacturing Engineering, National University of Science & Technology, Islamabad 44000, Pakistan.ORCID 0000-0002-1476-615X
California Medical Innovations Institute · USNortheastern University · US

Funding

Higher Education Commission, Pakistan 6035
6 · The paper itself

Abstract

Metallic nanoparticles, such as gold nanoparticles (AuNPs), have been extensively studied as drug delivery systems for various therapeutic applications. However, drug-loaded-AuNPs have been rarely explored in vivo for their effect on bacteria residing inside tissues. Ciprofloxacin (CIP) is a second-generation fluoroquinolone with a broad-spectrum of antibiotic properties devoid of developing bacteria resistance. This research is focused on the synthesis and physical characterization of Ciprofloxacin-loaded gold nanoparticles (CIP-AuNPs) and their effect on the colonization of

Indexed as

antibioticsantimicrobial resistanceciprofloxacindrug deliveryEnterococcus faecalisgold nanoparticlesliver and kidney infectionsnanotechnology

Identifiers

PMID34835916
PMCPMC8620493
OpenAlexW3215328942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.