Evidence map›Paper›PMID 34835710›Full record

ArticleNanomaterials (Basel, Switzerland)2021

Tween

Jason Thomas Duskey, Ilaria Ottonelli, Arianna Rinaldi, Irene Parmeggiani, Barbara Zambelli, Leon Z Wang, Robert K Prud'homme, Maria Angela Vandelli, Giovanni Tosi, Barbara Ruozi

Abstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Prospects and challenges of recombinant spider venom enzymes: insights fromFrontiers in bioengineering and biotechnology · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Tunneling Nanotubes: A New Target for Nanomedicine?International journal of molecular sciences · 2022
    Review
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jason Thomas DuskeyTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0003-2204-1981
Ilaria OttonelliTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-2135-2422
Arianna RinaldiTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Irene ParmeggianiTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Barbara ZambelliLaboratory of Bioinorganic Chemistry, Department of Pharmacy and Biotechnology, University of Bologna, 40127 Bologna, Italy.ORCID 0000-0002-3876-0051
Leon Z WangDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA.
Robert K Prud'hommeDepartment of Chemical and Biological Engineering, Princeton University, Princeton, NJ 08544, USA.
Maria Angela VandelliTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.
Giovanni TosiTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0001-8318-667X
Barbara RuoziTe.Far.T.I.-Nanotech Lab, Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-2400-9910

Funding

Creutzfeldt-Jakob disease Foundation 000Innovative Medicines Initiative 807015Ministero degli Affari Esteri e della Cooperazione Internazionale MAE00691612020-06-26
6 · The paper itself

Abstract

Enzymes, as natural and potentially long-term treatment options, have become one of the most sought-after pharmaceutical molecules to be delivered with nanoparticles (NPs); however, their instability during formulation often leads to underwhelming results. Various molecules, including the Tween

Indexed as

enzyme deliveryenzyme stabilizationnanomedicinepolymeric nanoparticlesTween® stabilization

Identifiers

PMID34835710
PMCPMC8625811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.