ReviewNanomaterials (Basel, Switzerland)2021
Direct and Indirect Genotoxicity of Graphene Family Nanomaterials on DNA-A Review.
Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 49 citations in OpenAlex.
- Exploring the Antimicrobial Efficacy of Graphene Oxide: Key Mechanisms and Future Directions.Pharmaceutics · 2026Review
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- Characterization and evaluation of the ability of graphene quantum dots to affect α-synuclein aggregation in synucleinopathy models.Science and technology of advanced materials · 2026Article
- Understanding the cellular uptake and genotoxic potential of industrial relevant nanomaterials utilizing electron microscopy and the ToxTracker assay in vitro.Mutagenesis · 2025Article
- Hybrid Alginate-Graphene Composites: Biochemical Features and Biomedical Potential.Marine drugs · 2025Article
- Tailoring the Synthesis Route of Reduced Graphene Oxide and Its Toxicological Effects on Allium cepa L.ACS omega · 2025Article
- Article
- The gut microbiome meets nanomaterials: exposure and interplay with graphene nanoparticles.Nanoscale advances · 2023Review
- Current research trends of nanomedicines.Acta pharmaceutica Sinica. B · 2023Review
- Multiple RNA Profiling Reveal Epigenetic Toxicity Effects of Oxidative Stress by Graphene Oxide Silver Nanoparticles in-vitro.International journal of nanomedicine · 2023Article
- Identification of circular RNAs expression pattern in caprine fetal fibroblast cells exposed to a chronic non-cytotoxic dose of graphene oxide-silver nanoparticle nanocomposites.Frontiers in bioengineering and biotechnology · 2023Article
- Potential Biomedical Limitations of Graphene Nanomaterials.International journal of nanomedicine · 2023Review
- A Review of in vivo Toxicity of Quantum Dots in Animal Models.International journal of nanomedicine · 2023Review
- Age- and Lifespan-Dependent Differences in GO Caused DNA Damage inInternational journal of molecular sciences · 2022Article
- Recent Advances in Nanomaterials of Group XIV Elements of Periodic Table in Breast Cancer Treatment.Pharmaceutics · 2022Review
- Recent biomedical advancements in graphene oxide- and reduced graphene oxide-based nanocomposite nanocarriers.Biomaterials research · 2022Review
- Role of Nanomaterials in the Fabrication of bioNEMS/MEMS for Biomedical Applications and towards Pioneering Food Waste Utilisation.Nanomaterials (Basel, Switzerland) · 2022Review
- Special Issue "The Genetic Changes Induced by Engineered Manufactured Nanomaterials (EMNs)".Nanomaterials (Basel, Switzerland) · 2022Article
- Genotoxicity of Graphene-Based Materials.Nanomaterials (Basel, Switzerland) · 2022Review
- PLATOX: Integrated In Vitro/In Vivo Approach for Screening of Adverse Lung Effects of Graphene-Related 2D Nanomaterials.Nanomaterials (Basel, Switzerland) · 2022Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Graphene family nanomaterials (GFNs), including graphene, graphene oxide (GO), reduced graphene oxide (rGO), and graphene quantum dots (GQDs), have manifold potential applications, leading to the possibility of their release into environments and the exposure to humans and other organisms. However, the genotoxicity of GFNs on DNA remains largely unknown. In this review, we highlight the interactions between DNA and GFNs and summarize the mechanisms of genotoxicity induced by GFNs. Generally, the genotoxicity can be sub-classified into direct genotoxicity and indirect genotoxicity. The direct genotoxicity (e.g., direct physical nucleus and DNA damage) and indirect genotoxicity mechanisms (e.g., physical destruction, oxidative stress, epigenetic toxicity, and DNA replication) of GFNs were summarized in the manuscript, respectively. Moreover, the influences factors, such as physicochemical properties, exposure dose, and time, on the genotoxicity of GFNs are also briefly discussed. Given the important role of genotoxicity in GFNs exposure risk assessment, future research should be conducted on the following: (1) developing reliable testing methods; (2) elucidating the response mechanisms associated with genotoxicity in depth; and (3) enriching the evaluation database regarding the type of GFNs, applied dosages, and exposure times.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.