Evidence map›Paper›PMID 34835553›Full record

ReviewNanomaterials (Basel, Switzerland)2021

Optimization of Nanoparticles for Smart Drug Delivery: A Review.

Lina Jia, Peng Zhang, Hongyan Sun, Yuguo Dai, Shuzhang Liang, Xue Bai, Lin Feng

Abstract readReview
In one paragraph

Review in Nanomaterials (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Targeting breast tumor extracellular matrix and stroma utilizing nanoparticles.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Editorial for Special Issue "Cancer Treatment via Nanotherapy".Nanomaterials (Basel, Switzerland) · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lina JiaSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.ORCID 0000-0003-3907-1052
Peng ZhangSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.
Hongyan SunSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.
Yuguo DaiSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.
Shuzhang LiangSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.ORCID 0000-0002-5770-9366
Xue BaiSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.ORCID 0000-0002-7078-6147
Lin FengSchool of Mechanical Engineering and Automation, Beihang University, Beijing 100191, China.ORCID 0000-0002-5158-3862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoparticle delivery systems have good application prospects in the treatment of various diseases, especially in cancer treatment. The effect of drug delivery is regulated by the properties of nanoparticles. There have been many studies focusing on optimizing the structure of nanoparticles in recent years, and a series of achievements have been made. This review summarizes the optimization strategies of nanoparticles from three aspects-improving biocompatibility, increasing the targeting efficiency of nanoparticles, and improving the drug loading rate of nanoparticles-aiming to provide some theoretical reference for the subsequent drug delivery of nanoparticles.

Indexed as

biocompatibilitydrug loading ratetargeting efficiency

Identifiers

PMID34835553
PMCPMC8622036

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.