Evidence map›Paper›PMID 34835425›Full record

ArticleMicroorganisms2021

Molecular Epidemiology of Multidrug-Resistant Uropathogenic

Laura M Contreras-Alvarado, Sergio Zavala-Vega, Ariadnna Cruz-Córdova, Juan Pablo Reyes-Grajeda, Gerardo Escalona-Venegas, Víctor Flores, Virginia Alcázar-López, José Arellano-Galindo, Rigoberto Hernández-Castro, Graciela Castro-Escarpulli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Incidence of biofilms among the multidrug resistant E. coli, isolated from urinary tract infections in the Nilgiris district, South India.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2023
    Article
  10. Article
  11. Article
  12. Comparative genomic analysis of uropathogenicFrontiers in microbiology · 2023
    Article
  13. Article
  14. Review
  15. Review
  16. Two Phenotypes ofInfection and drug resistance · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 2 countries.

Laura M Contreras-AlvaradoLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.ORCID 0000-0002-7638-8430
Sergio Zavala-VegaLaboratorio de Neuropatología, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, Ciudad de México 14269, Mexico.
Ariadnna Cruz-CórdovaLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.
Juan Pablo Reyes-GrajedaSubdirección de Desarrollo de Aplicaciones Clínicas, Instituto Nacional de Medicina Genómica, Ciudad de México 14610, Mexico.ORCID 0000-0001-6498-3286
Gerardo Escalona-VenegasLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.
Víctor FloresDepartment of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK.
Virginia Alcázar-LópezDepartamento de Laboratorio Clínico, Laboratorio Central, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.
José Arellano-GalindoLaboratorio de Virología Clínica y Experimental, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.
Rigoberto Hernández-CastroDepartamento de Ecología de Agentes Patógenos, Hospital General Dr. Manuel Gea González, Ciudad de México 4800, Mexico.ORCID 0000-0002-5656-0942
Graciela Castro-EscarpulliLaboratorio de Investigación Clínica y Ambiental, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Ciudad de México 11340, Mexico.ORCID 0000-0002-7496-8247
Juan Xicohtencatl-CortesLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.ORCID 0000-0003-2577-9973
Sara A OchoaLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, Ciudad de México 06720, Mexico.ORCID 0000-0002-5299-759X
Hospital Infantil de México Federico Gómez · MXHospital General Dr. Manuel Gea Gonzalez · MXInstituto Nacional de Neurología y Neurocirugía · MXInstituto Politécnico Nacional · MXNational Institute of Genomic Medicine · MXUniversity of Cambridge · GB

Funding

Hospital Infantil de México Federico Gómez HIM-2017-107 SSA.1421Hospital Infantil de México Federico Gómez HIM-2018-045 SSA. 1503Hospital Infantil de México Federico Gómez HIM-2019-038 SSA. 1592Hospital Infantil de México Federico Gómez HIM-2021-030
6 · The paper itself

Abstract

backgroundUropathogenic

aimThe present study describes the molecular epidemiology of UPEC O25b clinical strains based on their resistance profiles, virulence genes, and genetic diversity.

methodsResistance profiles were identified using the Kirby-Bauer method, including the phenotypic production of extended-spectrum β-lactamases (ESBLs) and metallo-β-lactamases (MBLs). The UPEC serogroups, phylogenetic groups, virulence genes, and integrons were determined via multiplex PCR. Genetic diversity was established using pulsed-field gel electrophoresis (PFGE), and sequence type (ST) was determined via multilocus sequence typing (MLST).

resultsUPEC strains (

conclusionUPEC O25b/ST131 harbors a wide genetic diversity of virulence and resistance genes, which contribute to cUTIs in pediatrics.

Indexed as

genetic diversityMDRMLSTUPEC O25

Identifiers

PMID34835425
PMCPMC8623209
OpenAlexW3212018997

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.