Evidence map›Paper›PMID 34835359›Full record

ArticleMicroorganisms2021

Flagella, Type I Fimbriae and Curli of Uropathogenic

Rubí Vega-Hernández, Sara A Ochoa, Ricardo Valle-Rios, Gustavo A Jaimes-Ortega, José Arellano-Galindo, Gerardo Aparicio-Ozores, José Antonio Ibarra, Rigoberto Hernández-Castro, Ariadnna Cruz-Córdova, Juan Xicohtencatl-Cortes

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.3field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 23 citations in OpenAlex.

  1. Loss of Type 1 Pili and Flagella in UropathogenicPathogens (Basel, Switzerland) · 2025
    Article
  2. Review
  3. Avian pathogenicVeterinary world · 2024
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Phenotypic and genotypic characteristics ofFrontiers in public health · 2023
    Article
  12. Genomic Characteristics of an Extensive-Drug-Resistant ClinicalIranian journal of pharmaceutical research : IJPR
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Rubí Vega-HernándezLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, 06720 Ciudad de México, Mexico.
Sara A OchoaLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, 06720 Ciudad de México, Mexico.ORCID 0000-0002-5299-759X
Ricardo Valle-RiosUnidad Universitaria de Investigación en Cáncer e Inmunología, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Ciudad de México, Mexico.
Gustavo A Jaimes-OrtegaUnidad Universitaria de Investigación en Cáncer e Inmunología, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, 04510 Ciudad de México, Mexico.
José Arellano-GalindoLaboratorio de Virología Clínica y Experimental, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de Mexico Federico Gómez, 06720 Ciudad de México, Mexico.
Gerardo Aparicio-OzoresDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, 11340 Ciudad de México, Mexico.
José Antonio IbarraDepartamento de Microbiología, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, 11340 Ciudad de México, Mexico.ORCID 0000-0002-5016-0622
Rigoberto Hernández-CastroDepartamento de Ecología de Agentes Patógenos, Hospital General Dr. Manuel Gea González, 4800 Ciudad de México, Mexico.ORCID 0000-0002-5656-0942
Ariadnna Cruz-CórdovaLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, 06720 Ciudad de México, Mexico.
Juan Xicohtencatl-CortesLaboratorio de Investigación en Bacteriología Intestinal, Unidad de Investigación en Enfermedades Infecciosas, Hospital Infantil de México Federico Gómez, 06720 Ciudad de México, Mexico.ORCID 0000-0003-2577-9973
Hospital Infantil de México Federico Gómez · MXInstituto Politécnico Nacional · MXHospital General Dr. Manuel Gea Gonzalez · MXUniversidad Autónoma Metropolitana · MX

Funding

Public Federal Funds from the Hospital Infantil de México Federico Gómez. HIM-2018-045 SSA 1503 and HIM-2018-049 SSA 150
6 · The paper itself

Abstract

backgroundUrinary tract infections (UTIs) are a public health problem in Mexico, and uropathogenic

aimThis study aimed to determine whether flagella-, type I fimbriae-, and curli-expressing UPEC induces the release of proinflammatory cytokines in an established coculture system.

methodsThe

resultsHigh concentrations of IL-6 and IL-8 were induced by the FimH and FliC proteins; however, these cytokines were detected in low concentrations in presence of CsgA. Compared with UPEC CFT073, CFT073Δ

conclusionThe FimH and FliC proteins are involved in IL-6 and IL-8 release in a coculture model of HTB-5 and HMC-1 cells.

Indexed as

adherencecoculturecytokinesfimbriaeUPEC

Identifiers

PMID34835359
PMCPMC8624364
OpenAlexW3209574614

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.