Evidence map›Paper›PMID 34835287›Full record

ArticleVaccines2021

Commensal

Michele Tomasi, Mattia Dalsass, Francesco Beghini, Ilaria Zanella, Elena Caproni, Laura Fantappiè, Assunta Gagliardi, Carmela Irene, Enrico König, Luca Frattini and 8 more

Abstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Bacterial Outer Membrane Vesicles in Potentiating Cancer Vaccines: Progress and Prospects.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Michele TomasiDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0002-9613-1720
Mattia DalsassDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0003-1712-1071
Francesco BeghiniDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0002-8105-9607
Ilaria ZanellaDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Elena CaproniDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0002-5731-8736
Laura FantappièToscana Life Sciences, 53100 Siena, Italy.
Assunta GagliardiToscana Life Sciences, 53100 Siena, Italy.ORCID 0000-0003-2700-2471
Carmela IreneDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Enrico KönigDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0002-1560-5948
Luca FrattiniDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Giulia MasettiDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Samine Jessica IsaacDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Federica ArmaniniDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.
Fabio CumboDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0003-2920-5838
Aitor Blanco-MíguezDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0001-7386-5572
Alberto GrandiToscana Life Sciences, 53100 Siena, Italy.
Nicola SegataDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.ORCID 0000-0002-1583-5794
Guido GrandiDepartment of Cellular, Computational and Integrative Biology, University of Trento, 38123 Trento, Italy.

Funding

European Research Council 340915European Research Council 834634
6 · The paper itself

Abstract

A large body of data both in animals and humans demonstrates that the gut microbiome plays a fundamental role in cancer immunity and in determining the efficacy of cancer immunotherapy. In this work, we have investigated whether and to what extent the gut microbiome can influence the antitumor activity of neo-epitope-based cancer vaccines in a BALB/c-CT26 cancer mouse model. Similarly to that observed in the C57BL/6-B16 model,

Indexed as

cancer vaccinesimmunotherapymicrobiomeOMVspersonalized medicine

Identifiers

PMID34835287
PMCPMC8619961

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.