Evidence map›Paper›PMID 34835280›Full record

ArticleVaccines2021

Retinal Vascular Events after mRNA and Adenoviral-Vectored COVID-19 Vaccines-A Case Series.

Christian Girbardt, Catharina Busch, Mayss Al-Sheikh, Jeanne Martine Gunzinger, Alessandro Invernizzi, Alba Xhepa, Jan Darius Unterlauft, Matus Rehak

Open access · goldAbstract readCase Reports
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
9.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Retinal Changes After COVID-19 Infection and COVID-19 Vaccination.International medical case reports journal · 2023
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Christian GirbardtDepartment of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-7843-9617
Catharina BuschDepartment of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.ORCID 0000-0002-6267-4663
Mayss Al-SheikhDepartment of Ophthalmology, University Hospital Zurich, 8091 Zurich, Switzerland.
Jeanne Martine GunzingerDepartment of Ophthalmology, University Hospital Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-9005-347X
Alessandro InvernizziEye Clinic, Department of Biomedical and Clinical Sciences "Luigi Sacco", Luigi Sacco Hospital, University of Milan, 20157 Milan, Italy.
Alba XhepaEye Clinic, Department of Biomedical and Clinical Sciences "Luigi Sacco", Luigi Sacco Hospital, University of Milan, 20157 Milan, Italy.ORCID 0000-0003-1847-8726
Jan Darius UnterlauftDepartment of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.
Matus RehakDepartment of Ophthalmology, University Hospital Leipzig Medical Center, 04103 Leipzig, Germany.
University Hospital Leipzig · DEUniversity Hospital of Zurich · CHThe University of Sydney · AUUniversity Hospital of Bern · CHUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo describe cases of retinal vascular events shortly after administration of mRNA or adenoviral-vectored COVID-19 vaccines.

designRetrospective, multicenter case series.

methodsSix cases of retinal vascular events shortly after receiving COVID-19 vaccines.

resultsA 38-year-old, otherwise healthy male patient presented with branch retinal arterial occlusion four days after receiving his second dose of SARS-CoV-2 vaccination with Comirnaty

conclusionThis case series describes six cases of retinal vascular events shortly after receiving mRNA or adenoviral-vectored COVID-19 vaccines. The short time span between received vaccination and occurrence of the observed retinal vascular events raises the question of a direct correlation. Our case series adds to further reports of possible side effects with potential serious post-immunization complications of COVID-19 vaccinations.

Indexed as

COVID-19 vaccinationpost-vaccinationretinal vascular complicationvascular complication

Identifiers

PMID34835280
PMCPMC8625395
OpenAlexW3214563392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.