ArticleVaccines2021
The Mediating Roles of Medical Mistrust, Knowledge, Confidence and Complacency of Vaccines in the Pathways from Conspiracy Beliefs to Vaccine Hesitancy.
Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
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Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- COVID-19 vaccine hesitancy: A Systematic review of cognitive determinants.Health promotion perspectives · 2023Pooled it
- Cognitive and behavioral determinants of HPV vaccination willingness and Behavior among female university students in Karnataka, India.Human vaccines & immunotherapeutics · 2026Article
- Impact of social media use on influenza vaccine hesitancy among pediatric healthcare workers: The mediating role of 3Cs.Human vaccines & immunotherapeutics · 2026Article
- Article
- A video-based educational intervention to improve vaccine acceptance for Schistosomiasis japonicum: A pre-post study using the 5C model in rural China.Human vaccines & immunotherapeutics · 2025Article
- [Pneumococcal vaccination in people aged 60 and over: relationships between vaccination intention, knowledge, and psychological reasons for the vaccination decision].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025Article
- COVID-19 Vaccine Hesitancy Among Various Segments of the Population in Turkey: A Literature Review.Vaccines · 2025Review
- Paranoia affected COVID-19 vaccine refusal by increasing beliefs in conspiracy theories and mistrust of science.Frontiers in psychology · 2025Article
- Experiences of discrimination and their impact on healthcare utilization: non-uptake of covid-19 vaccination.Frontiers in public health · 2025Article
- Understanding vaccine hesitancy through the lens of trust and the 3C model: evidence from Chinese General Social Survey 2021.Frontiers in public health · 2025Article
- The evolution of vaccine hesitancy through the COVID-19 pandemic: A semi-structured interview study on booster and bivalent doses.Human vaccines & immunotherapeutics · 2024Article
- Predictors of Medical Mistrust Among Surrogate Decision-Makers of Patients in the ICU at High Risk of Death: A Pilot Study.CHEST critical care · 2024Article
- Using cluster analysis to explore COVID-19 vaccine booster hesitancy by levels of medical mistrust in fully vaccinated US adults.Annals of medicine · 2024Article
- Conspiracy narratives and vaccine hesitancy: a scoping review of prevalence, impact, and interventions.BMC public health · 2024Article
- Development and validation of a multi-dimensional COVID-19 vaccine hesitancy questionnaire.Vaccine: X · 2023Article
- COVID-19 Vaccine Hesitancy Among Patients Recovered From COVID-19 Infection in Wuhan, China: Cross-Sectional Questionnaire Study.JMIR public health and surveillance · 2023Article
- The association of conspiracy beliefs and the uptake of COVID-19 vaccination: a cross-sectional study.BMC public health · 2023Article
- The effect of altruism on COVID-19 vaccination rates.Health economics review · 2023Article
- Factors influencing parents' hesitancy to vaccinate their children aged 5-11 years old against COVID-19: results from a cross-sectional study in Malaysia.Frontiers in public health · 2023Article
- Ethical and social insights into synthetic biology: predicting research fronts in the post-COVID-19 era.Frontiers in bioengineering and biotechnology · 2023Article
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Authors and funding
5 authors at 1 institution in 1 country.
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Abstract
backgroundVaccine hesitancy, associated with medical mistrust, confidence, complacency and knowledge of vaccines, presents an obstacle to the campaign against the coronavirus disease 2019 (COVID-19). The relationship between vaccine hesitancy and conspiracy beliefs may be a key determinant of the success of vaccination campaigns. This study provides a conceptual framework to explain the impact of pathways from conspiracy beliefs to COVID-19 vaccine hesitancy with regard to medical mistrust, confidence, complacency and knowledge of vaccines.
methodsA non-probability study was conducted with 1015 respondents between 17 April and 28 May 2021. Conspiracy beliefs were measured using the coronavirus conspiracy scale of Coronavirus Explanations, Attitudes, and Narratives Survey (OCEANS), and vaccine conspiracy beliefs scale. Medical mistrust was measured using the Oxford trust in doctors and developers questionnaire, and attitudes to doctors and medicine scale. Vaccine confidence and complacency were measured using the Oxford COVID-19 vaccine confidence and complacency scale. Knowledge of vaccines was measured using the vaccination knowledge scale. Vaccine hesitancy was measured using the Oxford COVID-19 vaccine hesitancy scale. Confirmatory factor analysis (CFA) was used to evaluate the measurement models for conspiracy beliefs, medical mistrust, confidence, complacency, and knowledge of vaccines and vaccine hesitancy. The structural equation modeling (SEM) approach was used to analyze the direct and indirect pathways from conspiracy beliefs to vaccine hesitancy.
resultsOf the 894 (88.1%) respondents who were willing to take the COVID-19 vaccine without any hesitancy, the model fit with the CFA models for conspiracy beliefs, medical mistrust, confidence, complacency and knowledge of vaccines, and vaccine hesitancy was deemed acceptable. Conspiracy beliefs had significant direct (
conclusionsThe sample in this study showed lower vaccine hesitancy, and this study identified pathways from conspiracy beliefs to COVID-19 vaccine hesitancy in China. Conspiracy beliefs had direct and indirect effects on vaccine hesitancy, and the indirect association was determined through medical mistrust, confidence, complacency, and knowledge of vaccines. In addition, both direct and indirect pathways from conspiracy beliefs to vaccine hesitancy were identified as intervention targets to reduce COVID-19 vaccine hesitancy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.