Evidence map›Paper›PMID 34835191›Full record

ArticleVaccines2021

Recombinant BCG-Prime and DNA-Boost Immunization Confers Mice with Enhanced Protection against

Shihoko Komine-Aizawa, Satoru Mizuno, Kazuhiro Matsuo, Takahiro Namiki, Satoshi Hayakawa, Mitsuo Honda

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Antigen 85B ofVaccines · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. The Induction of Antigen 85B-Specific CD8International journal of molecular sciences · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shihoko Komine-AizawaDepartment of Pathology and Microbiology, Division of Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan.ORCID 0000-0001-9417-0315
Satoru MizunoJapan BCG Laboratory, Tokyo 204-0022, Japan.
Kazuhiro MatsuoJapan BCG Laboratory, Tokyo 204-0022, Japan.
Takahiro NamikiNihon University School of Medicine, Tokyo 173-8610, Japan.ORCID 0000-0003-0356-1877
Satoshi HayakawaDepartment of Pathology and Microbiology, Division of Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan.ORCID 0000-0002-1022-1443
Mitsuo HondaDepartment of Pathology and Microbiology, Division of Microbiology, Nihon University School of Medicine, Tokyo 173-8610, Japan.
Nihon University · JPJapan BCG Laboratory · JP

Funding

JSPS KAKENHI 19K08939
6 · The paper itself

Abstract

The incidence of infections with nontuberculous mycobacteria (NTM) has been increasing worldwide. The emergence of multidrug-resistant NTM is a serious clinical concern, and a vaccine for NTM has not yet been developed. We previously developed a new recombinant Bacillus Calmette-Guérin (rBCG) vaccine encoding the antigen 85B (Ag85B) protein of

Indexed as

CD4+ T CellsCD8+ T CellsMycobacterium kansasiirecombinant BCG

Identifiers

PMID34835191
PMCPMC8618695
OpenAlexW3211076258

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.